The Effectiveness of Silodosin for Nocturnal Polyuria in Elderly Men With Benign Prostatic Hyperplasia: A Multicenter Study [PDF]
Purpose: To investigate improvement in nocturia and nocturnal polyuria in nocturnal polyuria patients after silodosin administration by using a 3-day frequency volume chart. Methods: This was a prospective multicenter study.
Young Won Kim+6 more
doaj +1 more source
Effect of Nebulisation with Dexmedetomidine versus Magnesium Sulphate on Haemodynamic Response to Laryngoscopy and Intubation and Incidence of Postoperative Sore Throat: A Randomised Clinical Trial [PDF]
Introduction: Laryngoscopy and endotracheal intubation are essential procedures in general anaesthesia but can induce sympathetic hyperactivity, leading to transient increase in blood pressure and Heart Rate (HR).
Fateh Pal Singh Gill, Chhaya Suryawanshi
doaj +1 more source
Otorhinolaryngological adverse effects of urological drugs
Purpose: To describe the otorhinolaryngological adverse effects of the main drugs used in urological practice. Materials and Methods: A review of the scientific literature was performed using a combination of specific descriptors (side effect, adverse ...
Nathalia de Paula Doyle Maia+2 more
doaj +1 more source
Dynamics of prostate protectors assortment in the state formulary of medicines of 1-9 issues
Prostatitis is one of the most frequent urology diseases of men of reproductive age. Recommendations for rational pharmacotherapy prostatitis are included into the State Formulary of Medicines, which is reviewed and updated annually. Thus, the aim of our
І. V. Gadyak, B. P. Hromovyk
doaj +1 more source
A pattern mixture model for a paired $2\times2$ crossover design [PDF]
When conducting a paired $2\times2$ crossover design, each subject is paired with another subject with similar characteristics. The pair is then randomized to the same sequence of two treatments. That is, the two subjects receive the first experimental treatment, and then they cross over and receive the other experimental treatment(s).
arxiv +1 more source
Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair [PDF]
A family of microRNAs, called the miR-15 family, which includes miR-195, are shown to be up-regulated during pathological cardiac remodeling and repress the expression of mRNAs required for cell proliferation and survival, with consequent loss of ...
Olson, Eric N., van Rooij, Eva
core +1 more source
α1L-adrenoceptors mediate contraction of human erectile tissue [PDF]
α1-adrenoceptor antagonists can impact upon sexual function and have potential in the treatment of erectile dysfunction. Human erectile tissue contains predominantly α1A-adrenoceptors, and here we examined whether contractions of this tissue are mediated
Campbell, Alistair+6 more
core +1 more source
Energy Transport and its Function in Heptahelical Transmembrane Proteins [PDF]
Photoproteins such as bacteriorhodopsin (bR) and rhodopsin (Rho) need to effectively dissipate photoinduced excess energy to prevent their damage. Another well-studied G protein-coupled receptor (GPCR) containing 7 transmembrane (TM) helices is the B2 adrenergic receptor (B2AR), for which energy dissipation paths have been linked with allosteric ...
arxiv
Although agonist binding in adrenergic receptors is fairly well understood and involves residues located in transmembrane domains 3 through 6, there are few residues reported that are involved in antagonist binding.
D. Waugh+6 more
semanticscholar +1 more source