Results 71 to 80 of about 94,283,903 (258)

Comparative analysis of beta-adrenergic receptor kinase and beta-arrestin mRNA expression in human cells.

open access: yes, 1993
Receptor phosphorylation is a key step in the process of rapid desensitization. beta-Adrenergic receptor kinase is a specific receptor kinase that is known to phosphorylate and induce desensitization of several G-coupled synaptic receptors only when they
Ambrosini G   +7 more
core   +1 more source

Potential value of slow‐wave sleep in management of chronic insomnia disorder

open access: yesSleep Research, EarlyView.
Abstract Chronic insomnia disorder (CID), acknowledged as the most common sleep disorder, has traditionally been diagnosed and managed with a focus on reducing sleep onset latency and extending total sleep duration. However, the critical importance of slow‐wave sleep (SWS), a key indicator of objective sleep quality, has been largely overlooked in ...
Liping Zhang   +4 more
wiley   +1 more source

Topical administration of adrenergic receptor pharmaceutics and nerve growth factor

open access: yes, 2010
Jena J SteinleDepartments of Ophthalmology and Anatomy and Neurobiology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN 38163, USAAbstract: Topical application of nerve growth factor (NGF) and adrenergic receptor ...
Jena J Steinle
core  

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

open access: yesSmall, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan   +13 more
wiley   +1 more source

Beta(2)-adrenergic receptor desensitization, internalization and phosphorylation in response to full and partial agonists

open access: yes, 1997
The objective of this study is to test the hypothesis that partial agonists produce less desensitization because they generate less of the active conformation of the $\beta\sb2$-adrenergic receptor ($\beta$AR) (R*) and in turn cause less $\beta$AR ...
January, Bridgette Goodwin
core   +1 more source

Beta-Adrenergic Agonists

open access: yes, 2010
Inhaled β2-adrenoceptor (β2-AR) agonists are considered essential bronchodilator drugs in the treatment of bronchial asthma, both as symptoms-relievers and, in combination with inhaled corticosteroids, as disease-controllers.
Michele Baroffio   +10 more
core   +1 more source

6‐Nitrodopamine as a Novel Mediator of Prostatic Smooth Muscle Function in Mouse and Human

open access: yesAndrology, EarlyView.
ABSTRACT Background Epithelium‐derived catecholamines contribute to local regulation of genitourinary smooth muscle function, but the role of the endogenous 6‐nitrodopamine (6‐ND) in the prostate remains unknown. Objectives To determine whether 6‐ND is produced by mouse and human prostate and its role in smooth muscle regulation.
Alline Araujo Curiel   +12 more
wiley   +1 more source

Rehabilitation options for patients with different types of urinary incontinence following transurethral surgery for benign prostatic hyperplasia

open access: yesВестник урологии
Introduction. Transurethral resection of the prostate (TURP) remains the gold standard surgical treatment for benign prostatic hyperplasia (BPH), while various endoscopic enucleation techniques are gaining increasing popularity. Despite the advantages of
E. A. Meshcheriakova   +8 more
doaj   +1 more source

Beta-adrenergic-mediated Cl secretion: evidence for additional non-cAMP-dependent pathway of effect

open access: yes, 1990
It has been suggested that beta-adrenergic receptor antagonists with intrinsic sympathomimetic activity, like pindolol, are weak partial agonists for beta-adrenergic-stimulated adenylyl cyclase activation.
M. J. Welsh   +2 more
core   +1 more source

Trends in glaucoma diagnosis and medical management in Germany: A nationwide claims data analysis over 10 years

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Analysing longitudinal trends in recorded diagnosis and medical management of glaucoma in Germany over a 10‐year period. Methods A retrospective cohort study using nationwide outpatient claims and prescription data from the German statutory health insurance system.
Somar M. Hasan   +8 more
wiley   +1 more source

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