Results 181 to 190 of about 116,135 (274)

β3‐AR/β‐arrestin2 Interaction Triggers Cardiac Fibrosis Through JNK/c‐Jun Pathway in Cardiac Fibroblasts

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Myocardial fibrosis (MF) is a critical pathological substrate of heart failure (HF), and β3‐adrenergic receptor (β3‐AR) has been implicated in cardiac remodelling with controversial roles. This study aimed to clarify the pro‐fibrotic mechanism of β3‐AR in cardiac fibroblasts and its association with β‐arrestin2‐mediated biased activation ...
Zhongcheng Xu, Min Zhu, Chun Zhou, Juncang Duan, Jian Ding, Jun Liu, Xuan Ying, Jie Wu, Yang Dong, Wenbiao Wang, Zhaohui Qiu   +10 more
wiley   +1 more source

Beta-3 Adrenoreceptor Agonist Mirabegron Improves Right Ventricular Function in a Rat Monocrotaline-Induced Pulmonary Hypertension Model. [PDF]

Pulm Circ
Mendes-Ferreira P, Tielemans B, Wagenaar A, Bouzin C, Adão R, Pokreisz P, De Mulder D, Leite-Moreira A, Brás-Silva C, Balligand JL, Dessy C, Delcroix M, Quarck R, Belge C.   +13 more
europepmc   +1 more source

Pre‐anaesthetic risk assessment and management of dogs with myxomatous mitral valve disease: a spectrum of care narrative review

Journal of Small Animal Practice, Volume 67, Issue 8, Page 663-679, August 2026.
Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon, L. Köster, E. Vettorato, A. H. Estrada   +3 more
wiley   +1 more source

Thermogenesis in Adipose Tissue: Adrenergic and Non-Adrenergic Pathways. [PDF]

Cells
Hossain MA, Poojari A, Rabiee A.
europepmc   +1 more source

Refined Division of Sleep Stages in the Mouse Based on Distributed Deep Electrodes and Underlying Infra‐Slow Oscillation

Journal of Sleep Research, Volume 35, Issue 4, August 2026.
ABSTRACT The mouse sleep is mostly recorded with only epidural electrodes and divided simply into NREM and REM stages. With the help of distributed intracerebral triplet electrodes, we searched for possible new electrophysiological signatures to characterise more specific sleep substages within the timeframe of seconds to tens of minutes.
Nanxiang Jin, Sara Häkli, Keerthana Malathi, Hennariikka Koivisto, Theodor Boc, Jonas Schimmel, Eric Castell‐Caubet, Irina Gureviciene, Heikki Tanila   +8 more
wiley   +1 more source

LABA in patients with stage I COPD and mild sleep apnea syndrome: a pilot study

Open Medicine, 2011
Kopitovic Ivan, Kojicic Marija, Drvenica Mirjana, Ilic Miroslav   +3 more
doaj   +1 more source

Therapeutic Potential of the β3-Adrenergic Receptor and Its Ligands in Cardiovascular Diseases. [PDF]

Int J Mol Sci
Kempiński M, Jańczak P, Porębska A, Zawadzka PS, Jastrzębska P, Granat MM, Wojciechowska M.   +6 more
europepmc   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, Volume 27, Issue 8, August 2026.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Rates and Predictors of Persistent LUTS Medication Use After Laser Enucleation of the Prostate. [PDF]

Low Urin Tract Symptoms
Filzmayer M, Traumann MI, Humke C, Müller MJ, Mandel PC, Kluth LA, Becker A, Chun FK, Kosiba M.   +8 more
europepmc   +1 more source

Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart

The Journal of Physiology, Volume 604, Issue 15, Page 6281-6301, 1 August 2026.
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba, Peter R. Levasseur, Samuel D. Newton, Khia Min Sabrina Koh, Paige C. Arneson‐Wissink, Xinxia Zhu, Peter Pham, Heike Mendez, Luke Whitcomb, Ariana Sattler, William R Woodward, Beth A. Habecker, Daniel L. Marks, Aaron J. Grossberg   +13 more
wiley   +1 more source