The FASEB Journal, Volume 40, Issue 7, 15 April 2026.Abnormal extracellular ATP levels cause lower urinary tract symptoms (LUTS). Here, we demonstrate that overexpression of ENTPD1 (CD39TG)—an ATP/ADP converting enzyme—reduces voiding frequency while increasing void volume. Conversely, ENTPD1 deficiency results in frequent, small‐volume voiding.
Zhaobo Luo +7 more
wiley +1 more source
Therapeutic Potential of the β3-Adrenergic Receptor and Its Ligands in Cardiovascular Diseases. [PDF]
Int J Mol SciKempiński M +6 more
europepmc +1 more source
The Regulation and Function of Hippo/YAP Pathway in Cancer
The FASEB Journal, Volume 40, Issue 7, 15 April 2026.Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh +3 more
wiley +1 more source
An updated meta-analysis of head-to-head trials comparing the efficacy, safety, and adherence of mirabegron and vibegron in overactive bladder. [PDF]
Medicine (Baltimore)Bai WZ, Zhou SY, Mou YY, Peng L, Li LL.
europepmc +1 more source
Cross-Talk Between Signaling and Transcriptional Networks Regulating Thermogenesis-Insights into Canonical and Non-Canonical Regulatory Pathways. [PDF]
Int J Mol SciSimka-Lampa K.
europepmc +1 more source
Mirabegron exhibits antibacterial and Immunomodulatory activities demonstrated by in vitro and in vivo studies. [PDF]
Sci RepAhmed EA, Abd-Eldayem AM.
europepmc +1 more source
Repurposed Systemic Pharmacologic Agents in Chronic Pain: Emerging Mechanistic and Clinical Insights. [PDF]
J Clin MedMcKenzie A +7 more
europepmc +1 more source
Biased Orthosteric Agonism and Allosteric Modulation: Emerging Strategies for Developing New Class of β-Agonists for Obstructive Airway Diseases. [PDF]
Am J Respir Cell Mol BiolShah SD, Deshpande DA.
europepmc +1 more source
Pharmacotherapy Risks in Rare Genetic Diseases: Cross-Referencing ACMG Secondary Findings v3.2 List With Clinical Databases. [PDF]
Clin Transl SciAllen JD, Duong BQ, Brady J, Arn P.
europepmc +1 more source
Long-acting β<sub>2</sub> agonist (LABA) with a long-acting muscarinic receptor antagonist (LAMA) promotes human airway smooth muscle (HASM) relaxation and circumvents β<sub>2</sub> adrenergic receptor tachyphylaxis. [PDF]
Respir ResJude J +5 more
europepmc +1 more source