Results 171 to 180 of about 945,289 (264)

Beyond Joint Hypermobility: Investigating Bladder Dysfunction in Hypermobile Ehlers‐Danlos Syndrome

open access: yesNeurourology and Urodynamics, Volume 45, Issue 8, Page 1687-1691, November 2026.
ABSTRACT Introduction and Objectives Hypermobile Ehlers‐Danlos Syndrome (hEDS) is the most common subtype of Ehlers‐Danlos Syndrome, a group of connective tissue disorders caused by collagen abnormalities. While musculoskeletal features of hEDS are well characterized, its impact on visceral organs, including the bladder, remains underexplored.
Marium Ansari   +5 more
wiley   +1 more source

Continuous Imaging of the Cardiac Cycle Metabolism With Hyperpolarized [1‐13C]Pyruvate

open access: yesNMR in Biomedicine, Volume 39, Issue 11, November 2026.
We present a continuous hyperpolarized 13C MRI framework for phase‐resolved imaging of myocardial metabolism throughout the entire cardiac cycle. By combining spectral‐spatial bicarbonate excitation with frequency‐shifted reconstruction of residual pyruvate signal, both metabolites are obtained from a single acquisition.
Mohsen Redda   +5 more
wiley   +1 more source

ATP Release and Purinergic Signaling Potentiate β-Adrenergic Effects on Brown Adipocytes. [PDF]

open access: yesActa Physiol (Oxf)
Tozzi M   +8 more
europepmc   +1 more source

Target‐Engagement Prediction From Molecular Structure, In Vitro and Animal Data: A Tutorial for Early Assessment of Clinical Drug Exposure and Therapeutic/Adverse Potential Using the ANDROMEDA and PLATO Software on the InSilicoTrials Platform

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 11, November 2026.
ABSTRACT The target‐engagement predictor, implemented within the InSilicoTrials cloud‐based, AI‐powered platform for model‐informed drug discovery and development, enables early exploration of time‐dependent pharmacological responses. Predictions can be generated using inputs ranging from molecular structure to in vitro, animal, and clinical data ...
Niccolò Totis   +16 more
wiley   +1 more source

Cutaneous‐only hypersensitivity reaction presumed due to intravenous administration of atracurium in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary There are limited case reports of hypersensitivity reactions to neuromuscular blocking agents (NMBAs) in veterinary species, and none describe cutaneous‐only signs. This case report describes a Grade 1 cutaneous‐only hypersensitivity reaction to atracurium in a 7‐year‐old dog undergoing general anaesthesia for cataract surgery with bilateral ...
Kar Yee Phoon, Rob Ward
wiley   +1 more source

Ephedrine for Reducing Onset Time of Rocuronium in Elderly Patients: A Randomised Study

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 10, November 2026.
ABSTRACT Introduction Onset time of rocuronium is prolonged in elderly patients compared to younger patients. Ephedrine reduces onset time of rocuronium in younger adults, but in elderly patients, the effect of ephedrine on onset time of rocuronium has not been investigated.
Matias Vested   +10 more
wiley   +1 more source

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