Results 261 to 270 of about 53,199 (316)

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

Inadvertent Salbutamol Overdose Presenting as Acute Toxicity. [PDF]

Cureus
Aslam SM, Shyllesh H A, Siddarth Ts V, Suhail K M, Kulkarni A.   +4 more
europepmc   +1 more source

The beta-adrenergic receptor survives solubilization in deoxycholate while forming a stable association with the agonist.

, 1984
Elly Nedivi, M. Schramm
openalex   +1 more source

A Review of Nanoparticle‐Based Astrocyte Modulation in CNS Disorders: Evaluating the Underexplored Potential of Intranasal Delivery

Nano Select, Volume 7, Issue 1, January 2026.
Nanoparticle‐driven nose‐to‐brain drug delivery offers a noninvasive approach to bypass the blood–brain barrier (BBB) and directly modulate reactive astrocytes in CNS disorders. This review highlights biodegradable nanoparticles for astrocyte modulation, enhancing drug bioavailability, sustained release, and neuroinflammation control.
Senamile M. Dlamini, Gillian D. Mahumane, Pradeep Kumar, Yahya E. Choonara   +3 more
wiley   +1 more source

Integrating GPCR Regulation and Calcium Dynamics in Airway Smooth Muscle Function: A Comprehensive Review. [PDF]

Cells
Roy S, Gangipangi VK, Sharma P, Hancock RE, Sharma P.   +4 more
europepmc   +1 more source

Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent .beta.-adrenergic agonist virtually specific for .beta.3 receptors. A promising antidiabetic and antiobesity agent

, 1992
Jonathan D. Bloom, Minu Dutia, Bernard D. Johnson, Allan Wissner, Michael Burns, Elwood Largis, Jo Alene Dolan, Thomas H. Claus   +7 more
openalex   +1 more source

Impact of Anesthesia Strategy on Infant Pulmonary Function Test Quality and Duration

Pediatric Pulmonology, Volume 61, Issue 1, January 2026.
ABSTRACT Introduction While chloral hydrate (CH) has been standard for infant pulmonary function testing (iPFT) sedation, CH shortages are necessitating use of different sedation approaches. We aimed to compare the safety, test duration, and test quality of alternative sedation strategies for iPFT.
Aditi K. Zaveri, Brian Yoho, Brian Blasiole, Erick Forno, Daniel J. Weiner, Kristina Gaietto   +5 more
wiley   +1 more source

Thyrotoxic Hypokalemic Periodic Paralysis: Pathophysiological Mechanisms. [PDF]

Endocrinol Metab (Seoul)
Qing G, Zakaria WNA, Rom FZM, Nik WNFHW, Zulkeflee HA, Rahim SNA.   +5 more
europepmc   +1 more source

Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts

, 2012
Stacey Tannheimer, Clifford D. Wright, M Salmon   +2 more
openalex   +1 more source

Activity‐restoring mutations in the histamine H3 receptor increase constitutive activity and reduce structural stability

Protein Science, Volume 35, Issue 1, January 2026.
Abstract The histamine H3 receptor (H3R) is a class A G protein‐coupled receptor (GPCR) that regulates neurotransmitter release in the central nervous system. Although structures of H3R in both inactive and active states have been elucidated, the functional roles of specific residues remain unclear.
Ami Nakajima, Hiroto Kaneko, Kosuke Oyama, Misumi Kuchiji, Ayane Itakura, Chiaki Arai, Mitsunori Shiroishi   +6 more
wiley   +1 more source