Results 41 to 50 of about 125,185 (333)
BMC Cancer, 2004 Background Previous research has indicated that at various organ sites there is a subset of adenocarcinomas that is regulated by beta-adrenergic and arachidonic acid-mediated signal transduction pathways.
Cakir Yavuz +3 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Millions of patients suffer from asthma worldwide. However, the first-line drugs used to treat asthma, namely, the beta-adrenergic receptors agonists (β-agonists), are not recommended for use as monotherapy because of their severe dose-related side ...
Simeng Chu +7 more
doaj +1 more source
β‐Agonist‐induced constitutive β2‐adrenergic receptor activity in bovine tracheal smooth muscle [PDF]
British Journal of Pharmacology, 2000 According to the two state receptor model, the β2‐adrenergic receptor (β2‐AR) isomerizes between an inactive state and a constitutively active state, which couples to the stimulatory G‐protein in the absence of agonist. In bovine tracheal smooth muscle (BTSM), we investigated the effect of short and long term β2‐AR activation by fenoterol on ...
de Vries, Berber +6 more
openaire +2 more sources
A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility "in vitro" [PDF]
, 2016 The progression of prostate cancer (PC) to a metastatic hormone refractory disease is the major contributor to the overall cancer mortality in men, mainly because the conventional therapies are generally ineffective at this stage. Thus, other therapeutic
Bolchi, Cristiano +8 more
core +2 more sources
Meat and Muscle Biology, 2022 To determine how Zn and ractopamine hydrochloride (RAC) supplementation affect the longissimus thoracis muscle proteome in beef cattle, 48 high percentage Angus steers (494±18.2 kg) were utilized in a 2×2 factorial study design.
Elisabeth J. Huff-Lonergan +4 more
doaj +2 more sources
Development and validation of Triticum phytobiological method as an alternative procedure for investigating in vivo acute toxicity on mice [PDF]
, 2017 The goal of this study was to validate an alternative method for determining in vivo acute toxicity using vegetal material instead of laboratory animals, starting from the phytobiological method known also as the Triticum technique.
Anghel, Adriana +5 more
core +4 more sources
Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions
British Journal of Clinical Pharmacology, EarlyView., 2023 Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius +2 more
wiley +1 more source
Cannabinoid Receptor Involvement in Stress-Induced Cocaine Reinstatement: Potential Interaction with Noradrenergic Pathways [PDF]
, 2012 This study examined the role of endocannabinoid signaling in stress-induced reinstatement of cocaine seeking and explored the interaction between noradrenergic and endocannabinergic systems in the process.
Hillard, Cecilia J. +6 more
core +2 more sources
Neural regulation of cancer: from mechanobiology to inflammation. [PDF]
, 2016 Despite recent progress in cancer research, the exact nature of malignant transformation and its progression is still not fully understood. Particularly metastasis, which accounts for most cancer death, is a very complex process, and new treatment ...
Kim, Tae-Hyung +2 more
core +2 more sources
MODERN POSSIBILITIES OF MEDICAL TREATMENT OF OVERACTIVE BLADDER IN WOMEN
Медицинский совет, 2017 Overactive bladder (OAB) is a serious urination disorder which affects at least 17% of the population above 40 years old, of which 56% are women and 44% are men. M-cholinoblockers are the first line therapy and the main treatment for OAB.
I. A. Apolikhina +3 more
doaj +1 more source