Results 41 to 50 of about 51,117 (269)

Sinigrin Enhanced Antiasthmatic Effects of Beta Adrenergic Receptors Agonists by Regulating cAMP-Mediated Pathways

Frontiers in Pharmacology, 2020
Millions of patients suffer from asthma worldwide. However, the first-line drugs used to treat asthma, namely, the beta-adrenergic receptors agonists (β-agonists), are not recommended for use as monotherapy because of their severe dose-related side ...
Simeng Chu, Wenjuan Liu, Yujie Lu, Menglin Yan, Yingying Guo, Nianwei Chang, Min Jiang, Gang Bai   +7 more
doaj   +1 more source

Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? [PDF]

, 2014
The authors acknowledge the medical writing assistance received from Sam Yarwood, PhD, of Complete HealthVizion, in the form of literature searches and preparation and revision of the draft manuscript.Peer reviewedPublisher ...
Fromer, Leonard, Kaplan, Alan, Price, David, Román-Rodríguez, Miguel, van der Molen, Thys   +4 more
core   +4 more sources

Human fat cell beta-adrenergic receptors: beta-agonist-dependent lipolytic responses and characterization of beta-adrenergic binding sites on human fat cell membranes with highly selective beta 1-antagonists.

Journal of Lipid Research, 1988
Beta-adrenergic receptors were characterized in human fat cell membranes using 125I-labeled cyanopindolol (125I-labeled CYP) and highly selective beta 1-antagonists. The iodinated radioligand bound saturably and specifically to a single class of high affinity binding sites.
MAURIEGE P, DE PERGOLA, Giovanni, BERLAN M, LAFONTAN M.   +3 more
openaire   +3 more sources

The Influence of Supplemental Zinc and Ractopamine Hydrochloride on the Performance and Longissimus Thoracis Proteome of Finishing Beef Steers

Meat and Muscle Biology, 2022
To determine how Zn and ractopamine hydrochloride (RAC) supplementation affect the longissimus thoracis muscle proteome in beef cattle, 48 high percentage Angus steers (494±18.2 kg) were utilized in a 2×2 factorial study design.
Elisabeth J. Huff-Lonergan, Elizabeth Messersmith, Katherine G. Hochmuth, Matthew D. Schulte, Stephanie L. Hansen   +4 more
doaj   +2 more sources

Development and validation of Triticum phytobiological method as an alternative procedure for investigating in vivo acute toxicity on mice [PDF]

, 2017
The goal of this study was to validate an alternative method for determining in vivo acute toxicity using vegetal material instead of laboratory animals, starting from the phytobiological method known also as the Triticum technique.
Anghel, Adriana, Chiriță, Cornel, Cristea, Aurelia N., Dinu, Mihaela, Olaru, Octavian, Ştefănescu, Emil   +5 more
core   +4 more sources

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress [PDF]

, 2015
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking.
A Cippitelli, A Cippitelli, A Cippitelli, A Ettenberg, A Ettenberg, A Plaza-Zabala, A Sekino, A Van't Veer, AC Hansson, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AE Higley, AM Chirila, AM Polter, AM Thierry, AN Carey, Anh D Lê, AS Kreibich, AY Deutch, B Boutrel, B Lee, B Ribeiro Do Couto, B Setlow, B Wang, B Wang, B Wang, B Wang, B Wang, BB Land, BH Westerink, BL Lewis, BM Cox, BR Lee, C Cifani, C Li, CD Schmoutz, CJ Sanchez, CJ Sanchez, CK Nielsen, CL Pickens, CP Ford, CP O'Brien, CR Gerfen, D Economidou, D Epstein, D Funk, D Funk, D Highfield, D Highfield, D Highfield, D Liu, D Rodaros, D Rotllant, David A Baker, DC Glass, DEJ Redmond, DH Epstein, DJ Calu, DJ Calu, DM Buffalari, DM Buffalari, DM Buffalari, Douglas Funk, DR Gehlert, DR Staub, DS Zahm, DT George, DW Schulz, DW Self, E Krupitsky, EA Stone, EB Margolis, EJ Khantzian, EN Graf, EN Graf, EP Zorrilla, EP Zorrilla, F Chaouloff, F Cohen, F Georges, F Leri, F Sedki, F Weiss, FC Cruz, FJ White, G Aston-Jones, G de Guglielmo, G Zislis, GF Koob, GP Chrousos, GR Valdez, H Selye, H Yamada, HC Fox, HC Fox, J Jenkins, J Stewart, J Wang, JA Deutch, JA Gray, JA Simms, JC Umhau, JD Bremner, JD Bremner, JD Shepard, JE LeDoux, JE Morley, JJ Anker, JJ Anker, JK Richards, JK Seamans, JL McGaugh, JM Blacktop, JM Bossert, JM Bossert, JM Bossert, JM Fritschy, JN Cleck, John R Mantsch, JP McLaughlin, JP Schroeder, JR Glowa, JR Mantsch, JR Mantsch, JR Mantsch, JR Mantsch, JR McReynolds, JR Schank, JR Schank, JR Schank, JV Aldrich, JV Aldrich, K McFarland, K Van Pett, KJ Jackson, KL Conrad, KL Shelton, L Lu, L Lu, L Lu, L Lu, L Zhou, LA Briand, LE Kwako, LG Kirby, LK Vaughn, M Davis, M Davis, M Heilig, M Sakanaka, MA Ungless, MB Bannon, MD Cassell, ME Bouton, ME Bouton, ME Carroll, MEP Seligman, MF Dallman, MK Greenwald, ML Jobes, ML Price, MM Moran-Santa Maria, MM Moran-Santa Maria, MR Bruchas, MR Bruchas, MT Stefanik, MW Feltenstein, MW Feltenstein, MW Hale, N Capriles, N Omelchenko, N Sidhpura, NA Chen, NM Graziane, O Vranjkovic, O Vranjkovic, P Enrico, PE Sawchenko, PJ Fletcher, PM Beardsley, PM Beardsley, PS Regier, PV Piazza, PW Kalivas, PW Kalivas, PW Kalivas, PW Marinelli, R Ciccocioppo, R Haynes, R Kvetnansky, R Martin-Fardon, R Mongeau, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Takahata, RC Pierce, RC Twining, RD Weiss, RE See, RE See, RJ Smith, RM Gold, RP Vertes, RP Vertes, RP Waters, RY Moore, S Cabib, S Cohen, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Fanous, S Geisler, S Grimwood, S Shiffman, S Stopponi, S Stopponi, S Stopponi, S Tobin, S Tobin, SA Flavin, SE Back, SF Maier, SF Maier, SG Nair, SG Nair, SG Nair, SH Ahmed, SH Ahmed, SL Grella, SM Antelman, SO Eans, SR Bornstein, SR Sesack, SV Mahler, SV Mahler, T Holdstock, T Maric, TL Bale, TR Kosten, U Shalev, U Shalev, U Shalev, U Shalev, U Shalev, U Shalev, UE Ghitza, V Deroche, VA Redila, WA Hunt, WB Cannon, WM Meil, X Liu, X Liu, X Wang, Y Buczek, Y Figueroa-Guzman, Y Nawata, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Silberman, Y Zhao, Yavin Shaham, YW Chen, YY Ma, YY Ma, Z Sarnyai, ZJ Brown, ZJ Brown, ZX Xi   +291 more
core   +2 more sources

MODERN POSSIBILITIES OF MEDICAL TREATMENT OF OVERACTIVE BLADDER IN WOMEN

Медицинский совет, 2017
Overactive bladder (OAB) is a serious urination disorder which affects at least 17% of the population above 40 years old, of which 56% are women and 44% are men. M-cholinoblockers are the first line therapy and the main treatment for OAB.
I. A. Apolikhina, A. S. Chochueva, A. S. Saidova, E. A. Gorbunova   +3 more
doaj   +1 more source

Is Misoprostol Cost-effective in the Prevention of Nonsteroidal Anti-inflammatory Drug—Induced Gastropathy in Patients With Chronic Arthritis? [PDF]

, 1994
Whether misoprostol, a synthetic prostaglandin E1 analogue, should be routinely prescribed along with nonsteriodal anti-inflammatory drugs (NSAIDS) to prevent gastric damage is of great clinical importance and has profound cost implications. No consensus
Johannesson, Magnus, Liang, Matthew H., Stucki, Gerold   +2 more
core   +1 more source

Late expression of alpha 2-adrenergic-mediated antilipolysis during differentiation of hamster preadipocytes.

Journal of Lipid Research, 1991
In order to study the ontogenesis of the beta- and alpha 2-adrenergic control of lipolysis during the adipose conversion process, a model based on preadipocytes isolated from the stromal-vascular fraction of hamster adipose tissue was developed.
JS Saulnier-Blache, M Dauzats, D Daviaud, D Gaillard, G Ailhaud, R Négrel, M Lafontan   +6 more
doaj   +1 more source

Regular treatment with formoterol for chronic asthma: serious adverse events [PDF]

, 2012
Epidemiological evidence has suggested a link between beta(2)-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are safe ...
Altman, Blauw, Cates, Cates, Cates, Cates, Ducharme, Greenstone, Higgins, Lipworth, Nelson, Ni Chroinin, Ni Chroinin, Pearce, Pearce, Salpeter, Walters, Walters   +17 more
core   +1 more source