Results 71 to 80 of about 92,710 (320)

The effect of β‐agonist on expression and trafficking of β2‐adrenergic receptors with N‐terminal polymorphisms

open access: yesThe FASEB Journal, 2008
The β2‐Adrenergic receptor (β2AR) is an important target for asthma medications. Stimulation of β2AR by agonist inhibits contractile processes and results in bronchodilation. Studies suggest that polymorphisms of the β2AR may act as disease modifiers.
Yulia A Koryakina   +3 more
openaire   +2 more sources

The heart, a secondary organ in the control of blood circulation

open access: yesExperimental Physiology, EarlyView., 2023
Abstract Circulation of the blood is a fundamental physiological function traditionally ascribed to the pressure‐generating function of the heart. However, over the past century the ‘cardiocentric’ view has been challenged by August Krogh, Ernst Starling, Arthur Guyton and others, based on haemodynamic data obtained from isolated heart preparations and
Branko Furst, José González‐Alonso
wiley   +1 more source

Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists. [PDF]

open access: yesPLoS ONE, 2011
Trace amine-associated receptors (TAAR) are rhodopsin-like G-protein-coupled receptors (GPCR). TAAR are involved in modulation of neuronal, cardiac and vascular functions and they are potentially linked with neurological disorders like schizophrenia and ...
Gunnar Kleinau   +8 more
doaj   +1 more source

BRONCHIAL ASTHMA THERAPY IN SMART-REGIME: STUDIES IN REAL CLINICAL PRACTICE

open access: yesМедицинский совет, 2016
Despite considerable progress in development of effective therapeutic means, numerous studies are indicative of the insufficient BA control level resulting in reduction of patient life quality as well as to the high risk of disease exacerbations.
R. S. FASSAKHOV
doaj   +1 more source

Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease

open access: yesDiscover Mental Health, 2023
Schizophrenia is a debilitating condition necessitating more efficacious therapies. Previous studies suggested that schizophrenia development is associated with aberrant synaptic pruning by glial cells.
Ellen R. Bowen   +10 more
doaj   +1 more source

Isoprenaline increases Excursive Restitution Slope in the Conscious Rabbit with Ischaemic Heart Failure [PDF]

open access: yesarXiv, 2009
Background: An increased QT/RR slope is hypothesized to be predictive of sudden cardiac death after myocardial infarction. Previous studies have shown that beta-adrenergic stimulation increases QT/RR slope, but the effects of beta-adrenergic stimulation on QT/RR slope in heart failure are unknown.
arxiv  

Allobaculum plays a predominant role in the activation of brown fat tissue by diallyl trisulfide

open access: yesFood Frontiers, EarlyView.
Diallyl trisulfide activates brown adipose tissue and prevents obesity by promoting the relative abundance of Allobaculum in the gut of mice. Oral supplementation of Allobaculum stercoricanis, a primary species in Allobaculum, activates brown adipose tissue and prevents obesity.
Yanzhou Hu   +10 more
wiley   +1 more source

An assay for beta-adrenergic receptors in isolated human fat cells.

open access: yesJournal of Lipid Research, 1982
The beta-adrenergic receptors have been characterized in isolated human adipocytes using a potent beta-adrenergic antagonist (-)-[3H]dihydroalprenolol.
P Engfeldt   +3 more
doaj  

Dynamic re-wiring of protein interaction: The case of transactivation [PDF]

open access: yesarXiv, 2006
We are looking at local protein interaction networks from the perspective of directed, labeled graphs with quantitative values for monotonic changes in concentrations. These systems can be used to perform stability analysis for a stable attractor, given initial values.
arxiv  

Anti-obesity effects of selective agonists to the beta 3-adrenergic receptor in dogs. II. Recruitment of thermogenic brown adipocytes and reduction of adiposity after chronic treatment with a beta 3-adrenergic agonist.

open access: yesJournal of Veterinary Medical Science, 1998
The aim of this study was to evaluate the effectiveness of beta 3-adrenergic agonists for the treatment and prevention of obesity in the dog. When a selective beta 3-adrenergic agonist, CL316,243 (0.1 mg/kg), was given orally to adult beagles every day ...
N. Sasaki   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy