Results 41 to 50 of about 44,105 (226)

Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease

open access: yesNeurobiology of Disease, 2020
Adrenergic systems regulate both cognitive function and immune function. The primary source of adrenergic signaling in the brain is norepinephrine (NE) neurons of the locus coeruleus (LC), which are vulnerable to age-related degeneration and are one of ...
Andrew K. Evans   +5 more
doaj  

Antidepressant-like Effects of Neuropeptide SF (NPSF) [PDF]

open access: yesWorld Journal of Research and Review (WJRR) ISSN:2455-3956, Volume-4, Issue-5, May 2017 Pages 26-30, 2020
Neuropeptide SF (NPSF) is a member of RFamide neuropeptides that play diverse roles in central nervous system. Little is know about the effects of NPSF on brain functions. Antidepressant-like effect of NPSF was studied in modified mice FST. NPSF showed the antidepressant-like effects by decreasing the immobility time and increasing the climbing and ...
arxiv  

The (--)[3H]dihydroalprenolol binding to rat adipocyte membranes: an explanation of curvilinear Scatchard plots and implications for quantitation of beta-adrenergic sites

open access: yesJournal of Lipid Research, 1982
In rat adipocyte membranes, both beta-adrenergic agonists and beta-adrenergic antagonists competed with (--)[3H]dihydroalprenolol for high affinity (KD 2-4 nM) and low capacity binding sites.
E M Dax, J S Partilla, R I Gregerman
doaj  

Beta-blocker exposure and survival outcomes in patients with advanced pancreatic ductal adenocarcinoma: a retrospective cohort study (BETAPANC)

open access: yesFrontiers in Pharmacology, 2023
Introduction: Preclinical studies have demonstrated the possible role of beta-adrenergic receptors in pancreatic ductal adenocarcinoma (PDAC) tumor invasion and migration.
Antoine Le Bozec   +11 more
doaj   +1 more source

Pepducins as a potential treatment strategy for asthma and COPD. [PDF]

open access: yes, 2018
Current therapies to treat asthma and other airway diseases primarily include anti-inflammatory agents and bronchodilators. Anti-inflammatory agents target trafficking and resident immunocytes and structural cells, while bronchodilators act to prevent or
Benovic, Jeffrey L.   +4 more
core   +2 more sources

Electrocardiographic Manifestations in three Psychiatric patients with Hypothermia – Case Report

open access: yesHellenic Journal of Cardiology, 2016
Hypothermia occurs when the core body temperature falls below 35°C, which, in severe cases, can lead to electrocardiographic changes. Several conditions that occur in the psychiatric population increase the risk of hypothermia.
Eleftherios Pelechas   +4 more
doaj   +1 more source

An assay for beta-adrenergic receptors in isolated human fat cells.

open access: yesJournal of Lipid Research, 1982
The beta-adrenergic receptors have been characterized in isolated human adipocytes using a potent beta-adrenergic antagonist (-)-[3H]dihydroalprenolol.
P Engfeldt   +3 more
doaj  

Anti-adrenergic effects of endothelin on human atrial action potentials are potentially anti-arrhythmic [PDF]

open access: yes, 2006
Endothelin-1 (ET-1) is elevated in patients with atrial fibrillation (AF) and heart failure. We investigated effects of ET-1 on human atrial cellular electrophysiological measurements expected to influence the genesis and maintenance of AF.
Kane, K.A.   +3 more
core   +1 more source

Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers

open access: yesActa Dermato-Venereologica, 2023
Parents of infants treated with beta-blockers for infantile haemangioma are often concerned about the long-term aesthetic outcome. This cross-sectional study assessed the influence on the long-term aesthetic outcome of characteristics of the infantile ...
Mireille M. Hermans   +12 more
doaj   +1 more source

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress [PDF]

open access: yes, 2015
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking.
A Cippitelli   +291 more
core   +2 more sources

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