Potential association between chronic alpha-1 adrenergic blockade and early epinephrine-related resuscitation profiles during cardiac arrest: a retrospective exploratory cohort study [PDF]
Frontiers in Cardiovascular MedicineBackground and objectivesEpinephrine remains central to advanced cardiac life support through combined alpha- and beta-adrenergic effects. Alpha-mediated vasoconstriction increases aortic diastolic and coronary perfusion pressures, while beta-adrenergic,
Reşad Beyoğlu, Filiz Özyiğit
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Beta-blocker use and outcome after allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia [PDF]
Annals of HematologyAllogeneic hematopoietic stem cell transplantation (HSCT) is curative for patients with acute myeloid leukemia (AML) through an immune-mediated graft-versus-leukemia effect, but relapse is common. Studies in solid tumors have shown that adrenergic stress
Johanna Werk +9 more
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Carvedilol, an Adrenergic Blocker, Suppresses Melanin Synthesis by Inhibiting the cAMP/CREB Signaling Pathway in Human Melanocytes and Ex Vivo Human Skin Culture [PDF]
International Journal of Molecular Sciences, 2020 Myoung Eun Choi, Hanju Yoo, Woo Jin Lee
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Adrenergic blocker terazosin potentially suppresses acetaminophen induced-acute liver injury in animal models via CYP2E1 gene [PDF]
Toxicological Research, 2022 Muhammad Saeed +2 more
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The influence of adrenoceptor blocker treatment on fracture healing in osteoporotic and non-osteoporotic bone [PDF]
Frontiers in PhysiologyFracture healing is a highly dynamic process that involves inflammation, cell recruitment, angiogenesis, and subsequent bone formation and remodeling.
Sandra Dieterich +9 more
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Biomedicines, 2022 Background: Presurgical treatment with an α-adrenergic receptor blocker is recommended to antagonize the catecholamine-induced α-adrenergic receptor mediated vasoconstriction in patients with pheochromocytoma or sympathetic paraganglioma (PPGL). There is,
Annika M. A. Berends +14 more
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A Meta-Analysis of Long- Versus Short-Acting Phosphodiesterase 5 Inhibitors: Comparing Combination Use With α-Blockers and α-Blocker Monotherapy for Lower Urinary Tract Symptoms and Erectile Dysfunction [PDF]
International Neurourology Journal, 2015 Purpose: Combination therapy with an α-1-adrenergic blocker and phosphodiesterase type 5 inhibitors (PDE5Is) has shown improvements in lower urinary tract symptoms (LUTS) with negligible side effects.
Hoon Choi +6 more
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Biomolecules, 2023 The combustion of fossil fuels contributes to air pollution (AP), which was linked to about 8.79 million global deaths in 2018, mainly due to respiratory and cardiovascular-related effects.
Antonio G. Soares +8 more
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Scientific Reports, 2021 Beta-cardiotoxin (β-CTX) from the king cobra venom (Ophiophagus hannah) was previously proposed as a novel β-adrenergic blocker. However, the involvement of β-adrenergic signaling by this compound has never been elucidated.
Tuchakorn Lertwanakarn +6 more
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Neurobiology of Disease, 2020 Adrenergic systems regulate both cognitive function and immune function. The primary source of adrenergic signaling in the brain is norepinephrine (NE) neurons of the locus coeruleus (LC), which are vulnerable to age-related degeneration and are one of ...
Andrew K. Evans +5 more
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