Results 11 to 20 of about 136,170 (301)

The roles of beta-adrenergic receptors in tumorigenesis and the possible use of beta-adrenergic blockers for cancer treatment: possible genetic and cell-signaling mechanisms

open access: yesCancer Management and Research, 2012
Khanh vinh quốc Lương, Lan Thi Hoàng NguyễnVietnamese American Medical Research Foundation, Westminster, California, USAAbstract: Cancer is the leading cause of death in the USA, and the incidence of cancer increases dramatically with age ...
Luong KV, Nguyen LT
doaj   +1 more source

Pharmaceuticals in the aquatic environment: β-blockers as a case study [PDF]

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 20/09/2008.The presence of many human pharmaceuticals in the aquatic environment is now a worldwide concern and yet little is known of the chronic effects ...
Giltrow, Emma
core   +7 more sources

The Impact of Beta-Blocker Use at the Time of Hematopoietic Cell Transplantation on the Development of Acute and Chronic Graft-Versus-Host Disease

open access: yesHematology/Oncology and Stem Cell Therapy, 2023
Sympathetic nervous system activation plays a role in the development of acute and chronic graft-versus-host disease (GVHD) following allogeneic hematopoietic cell transplantation (HCT).
Arjun Patel   +4 more
doaj   +1 more source

Transforming growth factor β₁ oppositely regulates the hypertrophic and contractile response to β-adrenergic stimulation in the heart. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Neuroendocrine activation and local mediators such as transforming growth factor-β₁ (TGF-β₁) contribute to the pathobiology of cardiac hypertrophy and failure, but the underlying mechanisms are incompletely understood.
Michael Huntgeburth   +13 more
doaj   +1 more source

THE PRINCIPLES OF USING ESMOLOL IN THE PRACTICE OF AN ANESTHESIOLOGIST AND AN INTENSIVE CARE PHYSICIAN

open access: yesКлінічна та профілактична медицина, 2021
Aim of the study: to analyze the problem of using the beta-1-blocker esmolol for anesthetic management and intensive care from the sources of the modern available literature. Materials and methods. Bibliosemantic, comparative and systems analysis. The
V. I. Cherniy   +2 more
doaj   +1 more source

Influence of β(1) Adrenergic Receptor Genotype on Longitudinal Measures of Left Ventricular Ejection Fraction and Responsiveness to ß-Blocker Therapy in Patients With Duchenne Muscular Dystrophy [PDF]

open access: yes, 2022
The purpose of this study was to determine whether the longitudinal progression of decline in left ventricular ejection fraction (LVEF) in Duchenne muscular dystrophy (DMD) patients is moderated by ADRB1 genotype and whether the efficacy of ß-blocker ...
Spurney, Christopher F   +12 more
core   +1 more source

Beta-Adrenergic Blockers [PDF]

open access: yesCirculation, 2003
beta-Adrenergic blocking drugs have been available for several years to treat ischemic heart disease and other cardiovascular and noncardiovascular disorders. There are multiple drugs in this class with various pharmacodynamic and pharmacokinetic properties that may be important in specific clinical situations and in avoiding certain adverse reactions.
openaire   +2 more sources

Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling [PDF]

open access: yes, 2014
Grazia Daniela Femminella,1 Vincenzo Barrese,2,3 Nicola Ferrara,1,4 Giuseppe Rengo4 1Department of Translational Medical Sciences, Federico II University, Naples, Italy; 2Department of Neuroscience, Reproductive Science and Odontostomatology, Federico II
Ferrara, N   +11 more
core   +1 more source

The β-blocker Nebivolol Is a GRK/β-arrestin Biased Agonist [PDF]

open access: yes, 2013
Nebivolol, a third generation β-adrenoceptor (β-AR) antagonist (β-blocker), causes vasodilation by inducing nitric oxide (NO) production. The mechanism via which nebivolol induces NO production remains unknown, resulting in the genesis of much of the ...
Jackson, Edwin K.   +36 more
core   +2 more sources

β-Adrenergic agonist and antagonist regulation of autophagy in HepG2 cells, primary mouse hepatocytes, and mouse liver. [PDF]

open access: yesPLoS ONE, 2014
Autophagy recently has been shown to be involved in normal hepatic function and in pathological conditions such as non-alcoholic fatty liver disease. Adrenergic signalling also is an important regulator of hepatic metabolism and function.
Benjamin L Farah   +6 more
doaj   +1 more source

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