Results 81 to 90 of about 2,328,761 (289)

The α2C-adrenergic receptor mediates hyperactivity of coloboma mice, a model of attention deficit hyperactivity disorder

open access: yesNeurobiology of Disease, 2006
Drugs that modify noradrenergic transmission such as atomoxetine and clonidine are increasingly prescribed for the treatment of attention deficit hyperactivity disorder (ADHD).
Kristy J. Bruno, Ellen J. Hess
doaj  

Dynamic re-wiring of protein interaction: The case of transactivation [PDF]

open access: yesarXiv, 2006
We are looking at local protein interaction networks from the perspective of directed, labeled graphs with quantitative values for monotonic changes in concentrations. These systems can be used to perform stability analysis for a stable attractor, given initial values.
arxiv  

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

open access: yesThe Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna   +15 more
wiley   +1 more source

Topical administration of adrenergic receptor pharmaceutics and nerve growth factor

open access: yesClinical Ophthalmology, 2010
Jena J SteinleDepartments of Ophthalmology and Anatomy and Neurobiology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN 38163, USAAbstract: Topical application of nerve growth factor (NGF) and adrenergic receptor ...
Jena J Steinle
doaj  

Detection in Molecular Communications with Ligand Receptors under Molecular Interference [PDF]

open access: yesarXiv, 2020
Molecular Communications (MC) is a bio-inspired communication technique that uses molecules to transfer information among bio-nano devices. In this paper, we focus on the detection problem for biological MC receivers employing ligand receptors to infer the transmitted messages encoded into the concentration of molecules, i.e., ligands.
arxiv  

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

open access: yesAnimal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li   +10 more
wiley   +1 more source

Preponderance of alpha 2- over beta 1-adrenergic receptor sites in human fat cells is not predictive of the lipolytic effect of physiological catecholamines

open access: yesJournal of Lipid Research, 1983
Adrenergic control of human fat cell lipolysis is mediated by two kinds of receptor sites that are simultaneously stimulated by physiological amines. To establish a correlation between the binding characteristics of the receptor and biological functions,
M Lafontan, M Berlan, A Villeneuve
doaj  

Acute cardiovascular effects associated with the use of prescription medications: A Danish nationwide screening study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim This study aims to conduct a hypothesis‐generating screening for acute cardiovascular effects of prescription medications. Methods This Danish nationwide screening study was conducted among incident cases of cardiovascular diseases, including myocardial infarction (MI), ischemic stroke (IS), heart failure (HF), venous thromboembolism (VTE),
Saad Hanif Abbasi   +4 more
wiley   +1 more source

Exposure to pseudoephedrine during pregnancy and major congenital malformations: Findings from a large population‐based cohort of pregnancies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of this study was to assess the risk of major congenital malformations following first‐trimester pseudoephedrine (PSE) exposure. Methods A population‐based observational cohort study was conducted on pregnancies of women aged 15–49 years, insured by Clalit Health Services in southern Israel, who gave birth or had elective ...
Saar Dor   +7 more
wiley   +1 more source

Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α2C Adrenergic Receptor

open access: yesCell Reports, 2019
Summary: Adrenergic G-protein-coupled receptors (GPCRs) mediate different cellular signaling pathways in the presence of endogenous catecholamines and play important roles in both physiological and pathological conditions.
Xiaoyu Chen   +24 more
doaj  

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