Results 231 to 240 of about 169,025 (300)

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source

Transactivation of the EGF receptor as a novel desensitization mechanism for G protein-coupled receptors, illustrated by dopamine D2-like and β₂ adrenergic receptors. [PDF]

Cell Mol Biol Lett
Kundu D, Min X, Wang S, Peng L, Tian X, Wang M, Kim KM.   +6 more
europepmc   +1 more source

Refined Division of Sleep Stages in the Mouse Based on Distributed Deep Electrodes and Underlying Infra‐Slow Oscillation

Journal of Sleep Research, EarlyView.
ABSTRACT The mouse sleep is mostly recorded with only epidural electrodes and divided simply into NREM and REM stages. With the help of distributed intracerebral triplet electrodes, we searched for possible new electrophysiological signatures to characterise more specific sleep substages within the timeframe of seconds to tens of minutes.
Nanxiang Jin, Sara Häkli, Keerthana Malathi, Hennariikka Koivisto, Theodor Boc, Jonas Schimmel, Eric Castell‐Caubet, Irina Gureviciene, Heikki Tanila   +8 more
wiley   +1 more source

Targeting α₁- and α₂-adrenergic receptors as a countermeasure for fentanyl-induced locomotor and ventilatory depression. [PDF]

Environ Toxicol Pharmacol
Shaykin JD, Denehy ED, Martin JR, Chandler CM, Luo D, Taylor CE, Sunshine MD, Turner JR, Alilain WJ, Prisinzano TE, Bardo MT.   +10 more
europepmc   +1 more source

Comparative Pharmacokinetics of Intranasal or Intramuscular Atipamezole in Unsedated Dogs and Efficacy for Reversal of Xylazine Sedation

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The objectives of this study were to evaluate ATIP pharmacokinetics (PK) in healthy Beagle dogs after IM and IN dosing (Phase I), and to compare the rate of reversal of IM versus IN routes for xylazine (XYL) sedation (Phase II). This study was comprised of two sequential, randomized, crossover experiments. The initial PK study dosed ATIP by IN
Vanessa E. Cowan, Vanessa R. Mitcham, Deborah L. Michel, Chloe Lyons, Juliet Kennedy, Yoana C. Reyes Morales, Jennifer M. Loewen, Alan L. Chicoine   +7 more
wiley   +1 more source

Pharmacokinetics of Intramuscular and Intravenous Glycopyrrolate in Juvenile New Zealand White Rabbits

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Glycopyrrolate is an alternative to atropine to treat bradyarrhythmias in anesthetized rabbits; however, there are no pharmacokinetic studies in the literature. Six female New Zealand White rabbits received glycopyrrolate 0.05 mg/kg intravenously (IV) in the cephalic vein or intramuscularly (IM) in a complete crossover design.
Jocelyn Marchiori, Andrea Sanchez, Kristen Messenger, Jennifer M. Reinhart, Hugues Beaufrère, Sonja Fonfara, Alexander Valverde, Yu Gu, Ron Johnson   +8 more
wiley   +1 more source

In Vitro Activation of Human Adrenergic Receptors and Trace Amine-Associated Receptor 1 by Phenethylamine Analogues Present in Food Supplements. [PDF]

Nutrients
Pinckaers NET, Blankesteijn WM, Mircheva A, Shi X, Opperhuizen A, Schooten FV, Vrolijk MF.   +6 more
europepmc   +1 more source

Modelling of chromatographic and electrophoretic behaviour of imidazoline and alpha adrenergic receptors ligands under different acid-base conditions. [PDF]

ADMET DMPK
Oljacic S, Križman M, Popovic-Nikolic M, Vovk I, Nikolic K, Agbaba D.   +5 more
europepmc   +1 more source

Effect of thymoquinone on acetic acid-induced visceral nociception in rats: role of central cannabinoid and α₂-adrenergic receptors. [PDF]

Vet Res Forum
Naderi S, Tamaddonfard E, Nafisi S, Soltanalinejad-Taghiabad F.   +3 more
europepmc   +1 more source