Results 101 to 110 of about 17,014 (180)

Translational progress and bottlenecks in neurotransmitter-cancer research [2000-2025]: an integrated bibliometric and interventional trial analysis. [PDF]

Transl Cancer Res
Zhang M, Sun W, Ma Y, Zheng JC, Wu Q, Gao G.   +5 more
europepmc   +1 more source

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

Kidney-Targeted Nanoparticle Delivery of Formoterol Mitigates Diabetic Kidney Disease without Adverse Cardiac Effects. [PDF]

ACS Pharmacol Transl Sci
Vallorz EL, Cleveland K, Scholpa NE, Mansour HM, Schnellmann J, Schnellmann RG.   +5 more
europepmc   +1 more source

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, Volume 24, Issue 3, Page 468-484, September 2026.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

Neuro-tumor interactions: Multi-dimensional mechanisms of neurotransmitter regulation in tumor immune evasion and metabolic reprogramming. [PDF]

World J Clin Oncol
Li ZK, Liao JL, Luo MR, Fang SJ, Huang WZ, Zhang DY.   +5 more
europepmc   +1 more source

Adaptation of White Adipocytes to Cooler Temperatures: Impacts on Energy Metabolism and Protein Acetylation

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Cultured white adipocytes exposed to 31°C undergo cell‐autonomous metabolic adaptation characterized by enhanced mitochondrial function and widespread remodeling of the mitochondrial acetylome. Acetyl‐proteomic and metabolomic profiling identified mitochondria‐associated proteins, including SHMT2 and PCCA, whose acetylation changes were linked to ...
Hiroyuki Mori, Hadla Hariri, William Moe, Sophia Durham, Yuridia Guzman, Emma Paulsson, Rachel C. Simmermon, Parth B. Bhanderi, Sydney K. Peterson, Mia J. Dickson, Charles R. Evans, Ormond A. MacDougald   +11 more
wiley   +1 more source

Pharmacological treatment of obsessive-compulsive disorder in children and adolescents: An overview. [PDF]

World J Clin Pediatr
Rajalakshmi AK, Pawar AKS, Baweja R.
europepmc   +1 more source

Vitamin B3 (Nicotinamide) Supplementation in Primary and Scleroderma‐Related Raynaud Phenomenon

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective The aim of this study was to explore if vitamin B3 (nicotinamide) supplementation is a safe and effective adjunctive therapy for patients with primary Raynaud phenomenon (RP) and scleroderma‐related RP. The effect of nicotinamide supplementation in human patients with RP has not been studied before.
Mogeshni Govender, Natalie Tomson, Johnny Fang, Mohamed Bakry, Raymond Liu, Kathleen Morrisroe, Ross Penglase, Kokum Dissanayake, Ted Tsai   +8 more
wiley   +1 more source

Pharmacological Interventions for Orthostatic Hypotension: A Systematic Review. [PDF]

Cureus
Verma A, Saraya E, Haque MS, Senaratne M, Khan S, Kasagga A, Malasevskaia IA.   +6 more
europepmc   +1 more source

Astrocyte reactivity modifies the effects of locus coeruleus norepinephrine‐related dysfunction on tau and its impact on cognition

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Animal models demonstrated that pharmacologically‐induced lesioning of the locus coeruleus (LC), the brain's primary source of norepinephrine, triggered astrocyte reactivity, exacerbating Alzheimer's disease (AD) pathology and cognitive deficits.
Prokopis C. Prokopiou, Maxime Van Egroo, Joost M. Riphagen, Marion Baillet, Nicholas J. Ashton, Shorena Janelidze, Reisa A. Sperling, Keith A. Johnson, Kaj Blennow, Oskar Hansson, Henrik Zetterberg, Heidi I. L. Jacobs   +11 more
wiley   +1 more source