Results 81 to 90 of about 17,014 (180)

Quantitative [¹⁸F]FDOPA PET/CT for the characterization of biochemical phenotypes in paraganglioma and pheochromocytoma. [PDF]

EJNMMI Rep
Dahlmann P, Onkes M, Kunte S, Auer MK, Disko U, Wang K, Lottspeich C, Stüfchen I, Schweizer JROL, Mansour N, Brendel M, Schmid-Tannwald C, Fischer A, Nölting S, Auernhammer CJ, Reincke M, Bidlingmaier M, Werner RA, Kroiss M, Völter F.   +19 more
europepmc   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider, Kelly A. Aromolaran, Michael C. Sanguinetti, Ademuyiwa S. Aromolaran   +3 more
wiley   +1 more source

Endocrinological aspects of sarcopenic obesity. [PDF]

Ann Med
Minnetti M, Poggiogalle E, Frigerio F, Piciocchi C, Pierantozzi G, Di Vincenzo O, Pinto A, Gianfrilli D, Isidori AM, Migliaccio S, Donini LM.   +10 more
europepmc   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 2151-2156, September 2026.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Recent Advances of Azobenzene-Based Photoresponsive Molecular Switches for Protein-Targeted Photopharmacology. [PDF]

Molecules
Jiang J, Yuan X, Hu L.
europepmc   +1 more source

Combination Pharmacotherapies for Obesity—Current Evidence and Future Directions

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Combination pharmacotherapy for obesity can enhance weight loss by targeting complementary neuroendocrine and metabolic pathways. Such benefits are largely additive but limited by tolerability, cost and access. This review outlines practical clinical archetypes and a research agenda for safer, more precise and durable combination strategies across ...
A. B. M. Kamrul‐Hasan, Arnav Kalra, Nitin Kapoor, Deep Dutta, Kunal Mahajan, Robin Maskey, Syed Abbas Raza   +6 more
wiley   +1 more source

Adipocyte Browning: A Promising Avenue in Anti-Obesity Therapy. [PDF]

Int J Mol Sci
Bae YA, Cheon HG.
europepmc   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, Volume 58, Issue 5, Page 1413-1444, September 2026.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

The Influence of Basic Therapy and New Drugs on NO-Dependent Mechanisms of Cardiac Destruction in Chronic Heart Failure. [PDF]

Biomedicines
Belenichev I, Popazova O, Goncharov O, Bukhtiyarova N, Ryzhenko V, Semenov D, Oliynyk S, Petakh P, Kamyshnyi O.   +8 more
europepmc   +1 more source

The Six Pillars of Lifestyle Medicine in MASLD: An Evidence‐Based Guide

Liver International Communications, Volume 7, Issue 3, September 2026.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide and is projected to affect more than 40% of adults by 2050. Although pharmacologic therapies are emerging, lifestyle modification remains the foundation of management.
Jigyasa Sharma, Kathleen Viveiros
wiley   +1 more source