New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells
OBJECTIVES: Transcription Factor 21 represses steroidogenic factor 1, a nuclear receptor required for gonadal development, sex determination and the regulation of adrenogonadal steroidogenesis.
Monica Malheiros França +3 more
doaj +1 more source
Adrenocortical neoplasms in children: Treatment and outcomes
Background: Adrenocortical tumors are rare tumors in children with a paucity of outcome data, especially in a resource-challenged setting. Materials and Methods: A retrospective study was conducted to evaluate the presentation, management, and outcomes ...
Vishesh Jain +9 more
doaj +1 more source
Pneumoperitoneum in two cats treated with trilostane for hypercortisolism
Abstract This report describes two cases of pneumoperitoneum in cats receiving treatment for hypercortisolism and diabetes mellitus. Both cats presented with abdominal distention and lethargy and diagnoses of pneumoperitoneum were radiographically confirmed.
Nicholas James Kelly +4 more
wiley +1 more source
Emerging methods for subtype differentiation in primary aldosteronism
Abstract Primary aldosteronism (PA) is a common cause of hypertension. Compared to patients with essential hypertension, untreated PA is associated with a two‐ to fourfold greater risk of cardiovascular disease, renal failure, and death. PA is caused by increased secretion of aldosterone from one adrenal gland in 30% of the patients and both adrenal ...
Oskar Ragnarsson +5 more
wiley +1 more source
novel insights into the genetics and pathophysiology of adrenocortical tumors [PDF]
International audienceAdrenocortical tumors (ACTs) are typically unilateral and can be classified as benign adrenocortical adenomas (ACAs) or malignant adrenocortical cancers (ACCs).
Drougat, Ludivine +3 more
core +7 more sources
Preclinical Cushing's syndrome in adrenal incidentalomas [PDF]
Adrenal tumors are usually diagnosed by clinical symptoms of hormone excess. The increasing use of ultrasound and computed tomography results in the detection of a substantial number of incidentally discovered adrenal tumors.
Allolio, B. +5 more
core
Gene expression profiling of human adrenocortical tumors using complementary deoxyribonucleic Acid microarrays identifies several candidate genes as markers of malignancy. [PDF]
International audienceThe aim of this study was to identify predictor sets of genes whose over- or underexpression in human sporadic adrenocortical tumors would help to identify malignant vs.
Baudin, Eric +13 more
core +4 more sources
Adrenal gland tumours. Different clinical presentations in three dogs: a case report
Three dogs were evaluated due to the presence of unilateral adrenal gland masses with or without clinical signs. Case 1 showed a unilateral non-functional adrenocortical adenoma, discovered accidentally while Case 2 presented a unilateral cortisol ...
A. Loste +6 more
doaj +1 more source
Pure oestrogen-secreting feminizing adrenocortical adenoma. [PDF]
A 6-year-old boy presented with gynaecomastia. There was no clinical or biochemical evidence of excessive androgenic or glucorticoid activity, but urinary oestrogen levels were raised. An adrenocortical adenoma, demonstrated by x-ray, was surgically removed. Oestrogen levels fell immediately.
E, Bhettay, F, Bonnici
openaire +2 more sources
ABSTRACT Double Cushing syndrome exists: exogenous steroid use can mask concurrent adrenal hypercortisolism. When symptoms persist and cortisol remains high after tapering or stopping prescribed glucocorticoids, an endogenous source is likely. Early recognition with ACTH testing, dexamethasone suppression, and adrenal imaging reduces misdiagnosis ...
Reza Amani‐Beni +4 more
wiley +1 more source

