Results 91 to 100 of about 4,627 (243)

A Dual-Hormone Closed-Loop Delivery System for Type 1 Diabetes Using Deep Reinforcement Learning [PDF]

arXiv, 2019
We propose a dual-hormone delivery strategy by exploiting deep reinforcement learning (RL) for people with Type 1 Diabetes (T1D). Specifically, double dilated recurrent neural networks (RNN) are used to learn the hormone delivery strategy, trained by a variant of Q-learning, whose inputs are raw data of glucose \& meal carbohydrate and outputs are dual-
arxiv  

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Higher Concentration of Adrenocorticotropic Hormone Predicts Post-Stroke Depression

Clinical Interventions in Aging, 2022
Yanyan Wang,1 He Wang,2 Wenzhe Sun,1 Jinfeng Miao,1 Wenwen Liang,1 Xiuli Qiu,1 Yan Lan,1 Chensheng Pan,1 Guo Li,1 Xin Zhao,1 Zhou Zhu,1 Suiqiang Zhu1 1Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and ...
Wang Y, Wang H, Sun W, Miao J, Liang W, Qiu X, Lan Y, Pan C, Li G, Zhao X, Zhu Z, Zhu S   +11 more
doaj  

Clinical Presentation of Congenital Hypopituitarism: Lessons From a Large Academic Centre

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Pituitary hormone deficiencies are associated with considerable morbidity, yet the variability of presentation and evolution of congenital hypopituitarism remains unexplored. This study investigated differences in presentation of congenital isolated pituitary hormone deficiency (cIPHD) versus congenital multiple pituitary hormone ...
Jennifer M. Ladd, Amy L. Pyle‐Eilola, Leena Mamilly, Monika Chaudhari, Rohan K. Henry   +4 more
wiley   +1 more source

Systematic Review and Meta‐Analysis on the Prevalence of Radiotherapy‐Induced Hypopituitarism in Adults With Primary Non‐Pituitary Brain Tumours

Clinical Endocrinology, EarlyView.
ABSTRACT Context It is well recognised there is a high prevalence of pituitary dysfunction in childhood brain tumours survivors who are treated with radiotherapy. In contrast, the potential for survivors of brain tumours arising in adulthood to develop radiotherapy‐induced hypopituitarism may be underestimated.
Darran Mc Donald, Maria Tomkins, Liam O'Connell, David Fitzpatrick, Clare Faul, Michael W. O'Reilly, Kathleen Bennett, Mark Sherlock   +7 more
wiley   +1 more source

Utilizing of protein splicing phenomenon for optimization of obtaining and purification of the recombinant human growth hormone [PDF]

Europ J Medic Res., 2006, Oct. 8, vol.11 - p. 128-129, 2006
Protein splicing is a post-translational autocatalystic excision of internal protein sequence (intein) with the subsequent ligation of the flanking polypeptides (exteins). The high specificity of excision ensured by intein makes it possible to use a phenomenon of protein splicing for the biotechnology purposes.
arxiv  

Tools to Predict Unilateral Primary Aldosteronism and Optimise Patient Selection for Adrenal Vein Sampling: A Systematic Review

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Primary aldosteronism (PA), the most common endocrine cause of hypertension, is evaluated using adrenal vein sampling (AVS), to determine if aldosterone excess is bilateral or unilateral. AVS is invasive and technically challenging; it would ideally be used only in those with unilateral PA who are candidates for surgical cure.
Elisabeth Ng, Stella May Gwini, Winston Zheng, Peter J. Fuller, Jun Yang   +4 more
wiley   +1 more source

Cortisol response to low dose versus standard dose (back-to-back) adrenocorticotrophic stimulation tests in children and young adults with thalassemia major

Indian Journal of Endocrinology and Metabolism, 2013
Background: Thalassemia major patients with repeated blood transfusion have high prevalence of endocrinopathies due to iron overload. Materials and Methods: We examined the adrenocortical function in 23 thalassemic patients (10 children and 13 young ...
Ashraf T Soliman, Mohamed Yassin, Nadra M. S. Abdel Majuid, Aml Sabt, Mohamed O Abdulrahman, Vincenzo De Sanctis   +5 more
doaj   +1 more source

Numerical bifurcation analysis of pattern formation in a cell based auxin transport model [PDF]

arXiv, 2012
Transport models of growth hormones can be used to reproduce the hormone accumulations that occur in plant organs. Mostly, these accumulation patterns are calculated using time step methods, even though only the resulting steady state patterns of the model are of interest. We examine the steady state solutions of the hormone transport model of Smith et
arxiv  

EFFECT OF PITUITARY ADRENOCORTICOTROPIC AND GROWTH HORMONES ON THE RESISTANCE OF RATS INFECTED WITH PASTEURELLA PESTIS [PDF]

, 1957
Tetsuo Hayashida
openalex   +1 more source