Results 101 to 110 of about 1,081,498 (369)

Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and -independent mechanisms

Kidney International, 2013
Adrenocorticotropic hormone (ACTH) has a renoprotective effect in chronic kidney disease; however, its effect on acute kidney injury (AKI) remains unknown. In a rat model of tumor necrosis factor (TNF)–induced AKI, we found that ACTH gel prevented kidney
Jin Si, Y. Ge, S. Zhuang, Li Juan Wang, Shan Chen, R. Gong   +5 more
semanticscholar   +1 more source

An Excellent Clinical and Radiological Response Pattern to Pembrolizumab in a Patient With Metastatic Adrenocortical Carcinoma and Lynch Syndrome

IJU Case Reports, EarlyView.
ABSTRACT Introduction The prognosis of unresectable metastatic adrenocortical carcinoma is very poor. We report a case of Lynch syndrome accompanying metastatic adrenocortical carcinoma treated with pembrolizumab. Case Presentation A 73‐year‐old woman was diagnosed with left adrenocortical carcinoma and multiple lung, liver, and lymph node metastases ...
Yuki Shimozawa, Yosuke Yasuda, Emiko Sugawara, Ryosuke Oki, Kosuke Takemura, Tetsuya Urasaki, Ryo Fujiwara, Noboru Numao, Junji Yonese, Takeshi Yuasa   +9 more
wiley   +1 more source

Cushing's syndrome due to adrenocorticotropic hormone-secreting pheochromocytoma

CHRISMED Journal of Health and Research, 2016
Adrenocorticotropic hormone (ACTH) producing pheochromocytoma is the rare cause of Cushing's syndrome (CS). Herein, we present a 53-year-old female patient with ectopic ACTH-dependent Cushing's syndrome due to pheochromocytoma.
G V Chanukya, Manoj Mengade, Babu Reddy
doaj   +1 more source

Trilostane in dogs [PDF]

, 2010
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism.
Alenza, Angles, Baker, Barker, Bell, Benchekroun, Biller, Boag, Braddock, Cerundolo, Chapman, Clemente, Dewis, Dunn, Eastwood, Feldman, Galac, Galac, Golden, Goy-Thollot, Guptill, Hurley, Ian K. Ramsey, Kenefick, Kintzer, Komanicky, Leone, Lorenz, Machida, Mantis, McGee, McGowan, McGrotty, Neiger, Neiger, Neuman, Peterson, Potts, Puddefoot, Ramsey, Ramsey, Randolph, Reusch, Robinson, Ruckstuhl, Semple, Semple, Sieber-Ruckstuhl, Sieber-Ruckstuhl, Skelly, Tebb, Teshima, Tueni, Vaughan, Wenger, Wilbur, Williams, Winterberg, Witt, Zeugswetter   +59 more
core   +1 more source

Multiple Sclerosis, Relapses, and the Mechanism of Action of Adrenocorticotropic Hormone

Frontiers in Neurology, 2013
Relapses in multiple sclerosis (MS) are disruptive and frequently disabling for patients, and their treatment is often a challenge to clinicians. Despite progress in the understanding of the pathophysiology of MS and development of new treatments for ...
A. P. Ross, A. Ben-Zacharia, C. Harris, Jennifer Smrtka   +3 more
semanticscholar   +1 more source

Immediate Therapeutic Response to Vigabatrin in Lissencephaly‐Related Epileptic Spasms due to TUBA1A R402H Variant

American Journal of Medical Genetics Part A, EarlyView.
Toru Nagata, Takashi Shibata, Hiroki Tsuchiya, Mari Akiyama, Mitsuhiro Kato, Tomoyuki Akiyama, Toshiki Takenouchi   +6 more
wiley   +1 more source

Histopathological Features of the Testes of a Patient With Congenital Lipoid Adrenal Hyperplasia

IJU Case Reports, EarlyView.
ABSTRACT Introduction Congenital lipoid adrenal hyperplasia (CLAH) is a type of congenital adrenal hyperplasia characterized by reduced steroid production. Patients with this endocrine disorder as well as chromosome 46,XY have testes and female external genitalia. Because these individuals are usually raised as female, the testes are removed.
Takuya Sakata, Kentaro Mizuno, Daisuke Matsumoto, Hidenori Nishio, Atsushi Suzuki, Kohei Aoyama, Atsushi Ishida, Takahiro Yasui, Haruo Mizuno, Yutaro Hayashi   +9 more
wiley   +1 more source

Internal jugular vein: Peripheral vein adrenocorticotropic hormone ratio in patients with adrenocorticotropic hormone-dependent Cushing′s syndrome: Ratio calculated from one adrenocorticotropic hormone sample each from right and left internal jugular vein during corticotrophin releasing hormone stimulation test

Indian Journal of Endocrinology and Metabolism, 2013
Background: Demonstration of central: Peripheral adrenocorticotropic hormone (ACTH) gradient is important for diagnosis of Cushing′s disease. Aim: The aim was to assess the utility of internal jugular vein (IJV): Peripheral vein ACTH ratio for diagnosis ...
Sachin Chittawar, Saptarshi Bhattacharya, Jai Prakash Sahoo, Siva Prakash, Ashu Seith Bhalla, Devasenathipathy Kandasamy, Arundeep Arora, Nandita Gupta, Nikhil Tandon, Ravinder Goswami, Rajesh Khadgawat, Viveka P Jyotsna, Ashish Kumar Karak, Chandra Sekhar Bal, Ravindra Mohan Pandey, Guresh Kumar, Ariachery C Ammini   +16 more
doaj   +1 more source

Critical roles of endogenous glucocorticoids for disease tolerance in malaria

, 2019
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien, Opdenakker, Ghislain, Van den Steen, Philippe E., Vandermosten, Leen, Vanhorebeek, Ilse   +4 more
core   +1 more source

Persistent isolated hypocortisolism following brief treatment with trilostane [PDF]

, 2008
A 12-year-old male neutered Miniature Poodle with confirmed pituitary-dependent hyperadrenocorticism was treated with trilostane. After three doses, it developed clinical and laboratory changes suggestive of isolated hypocortisolism ('atypical ...
Barker, Bell, Braddock, Chapman, Dunn, Eastwood, Feldman, Hoffman, Javadi, Kintzer, Lifton, Mantis, Neiger, Rao, Ruckstuhl, Russell, Sadek, Sieber-Ruckstuhl, Wenger, Witt   +19 more
core   +1 more source