Results 101 to 110 of about 18,670 (220)

High Serum Adrenomedullin and Mid-Regional Pro-Atrial Natriuretic Peptide Concentrations in Early Pregnancy Predict the Development of Gestational Hypertension

open access: yesDiagnostics
Objectives: Adrenomedullin (AM) and natriuretic peptide levels are elevated in pre-eclampsia. The aim of the present study was to determine AM and natriuretic peptide concentrations before 20 weeks of pregnancy in women who later developed gestational ...
Aleksandra Jagodzinska   +3 more
doaj   +1 more source

Adrenomedullin expression in a rat model of acute lung injury induced by hypoxia and LPS [PDF]

open access: yes, 2005
Adrenomedullin (ADM) is upregulated independently by hypoxia and LPS, two key factors in the pathogenesis of acute lung injury (ALI). This study evaluates the expression of ADM in ALI using experimental models combining both stimuli: an in vivo model
Agorreta, J. (Jackeline)   +3 more
core  

A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure [PDF]

open access: yes, 2017
Aims: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes.
Bloomfield, Daniel M.   +17 more
core   +2 more sources

Safety, Tolerability, and Pharmacokinetics of Adrenomedullin in Healthy Males: A Randomized, Double-Blind, Phase 1 Clinical Trial

open access: yesDrug Design, Development and Therapy, 2020
Toshihiro Kita,1 Yoshikazu Kaji,2 Kazuo Kitamura1 1Division of Circulatory and Body Fluid Regulation, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan; 2Souseikai Hakata Clinic, Fukuoka, JapanCorrespondence ...
Kita T, Kaji Y, Kitamura K
doaj  

Hyperplasia of alveolar neuroendocrine cells in rat lung carcinogenesis by silica with selective expression of proadrenomedullin-derived peptides and amidating enzymes [PDF]

open access: yes, 2001
Pulmonary neuroendocrine (NE) cells are found as clusters called neuroepithelial bodies (NEBs) or as single cells scattered in the respiratory epithelium.
Blanco, D. (D.)   +5 more
core   +1 more source

Protective Effects of Adrenomedullin on Rat Cerebral Tissue After Transient Bilateral Common Carotid Artery Occlusion and Reperfusion

open access: yesBrazilian Journal of Cardiovascular Surgery
Objective: We aimed to investigate the protective effect of adrenomedullin (ADM) on cerebral tissue of rats with cerebral ischemia/reperfusion (I/R) injury. Methods: Thirty-two Wistar rats were randomized into four groups (n=8).
Mehmet Kirisci   +8 more
doaj   +1 more source

Prospective evaluation of biomarkers for prediction of quality of life in community-acquired pneumonia [PDF]

open access: yes, 2016
Most clinical research investigated prognostic biomarkers for their ability to predict cardiovascular events or mortality. It is unknown whether biomarkers allow prediction of quality of life (QoL) after survival of the acute event.
Beat Mueller   +9 more
core   +1 more source

Expression of proadrenomedullin derived peptides in the mammalian pituitary: co-localization of follicle stimulating hormone and proadrenomedullin N-20 terminal peptide-like peptide in the same secretory granules of the gonadotropes [PDF]

open access: yes, 2000
Expression of proadrenomedullin-derived peptides in the rat, cow and human pituitary was studied by a variety of techniques. Immunocytochemical detection showed a widespread expression of adrenomedullin peptide in the adenohypophysis and the neural lobe,
Burrell, M.A. (M.A.)   +10 more
core  

Expression of adrenomedullin and its receptor during embryogenesis suggests autocrine or paracrine modes of action [PDF]

open access: yes, 1997
The present study reports the developmental patterns of expression of adrenomedullin (AM) in rat and mouse embryos. AM is a novel multifunctional peptide recently isolated from a human pheochromocytoma, which has been shown to promote growth in a variety
Cuttitta, F. (Frank)   +4 more
core   +1 more source

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