Results 11 to 20 of about 11,146 (212)

Effects of hemodialysis on circulating adrenomedullin concentrations in patients with end-stage renal disease [PDF]

open access: yes, 1998
To characterize the determinants of circulating levels of adrenomedullin (AM), the plasma levels of this peptide were measured in 58 patients with end-stage renal disease on hemodialysis, Predialysis plasma levels of AM were more than twice as high in ...
Schlosshauer, M.   +5 more
core   +1 more source

Adrenomedullin and diabetes

open access: yesWorld Journal of Diabetes, 2014
Adrenomedullin (ADM) is a peptide hormone widely expressed in different tissues, especially in the vasculature. Apart from its vasodilatatory and hypotensive effect, it plays multiple roles in the regulation of hormonal secretion, glucose metabolism and inflammatory response.
Cheung, TT   +3 more
openaire   +4 more sources

Adrenomedullin alleviates mucosal injury in experimental colitis and increases claudin‐4 expression in the colonic epithelium

open access: yesFEBS Open Bio, 2023
Adrenomedullin (AM) is a peptide with pleiotropic physiological functions that attenuates intestinal mucosal inflammation. However, the mechanism underpinning mucosal protection by AM is not fully understood, and its effect on intestinal epithelial cells
Makiko Kawaguchi   +6 more
doaj   +1 more source

Endoglin and Activin Receptor-like Kinase 1 (Alk1) Modify Adrenomedullin Expression in an Organ-Specific Manner in Mice

open access: yesBiology, 2022
Hereditary hemorrhagic telangiectasia (HHT) is a rare disease characterized by vascular malformations and profuse bleeding. The disease is caused by mutations in the components of the BMP-9 receptor: endoglin (ENG) and activin receptor-like kinase 1 ...
Josune García-Sanmartín   +3 more
doaj   +1 more source

Adrenomedullin in patients with type 2 diabetes and kidney disease

open access: yesAfrican Journal of Nephrology, 2009
Secreting vasoactive factors such asadrenomedullin (AM) has been intensively investigated due to its vascular protective properties and promising potential as a therapeutic target.
Emam Waked   +5 more
doaj   +1 more source

Apocrine glands in the eyelid of primates contribute to the ocular host defense [PDF]

open access: yes, 2004
Apocrine glands of Moll are regular components of primate eyelids. We studied the distribution and localization of these glands in three different primate species, the common marmoset, the rhesus monkey, and the hamadryas baboon.
Stoeckelhuber, B. M.   +2 more
core   +1 more source

20 kDa PEGylated Adrenomedullin as a New Therapeutic Candidate for Inflammatory Bowel Disease

open access: yesGastrointestinal Disorders, 2020
Human adrenomedullin (AM), a hypotensive peptide, also has anti-colitis activity. We prepared a polyethylene glycol (PEG) ylated form of AM through the conjugation of PEG-AM (1–15) and AM (15–52).
Goro Miki   +10 more
doaj   +1 more source

Effect of magnesium sulfate treatment on mediators of endothelial dysfunction and electrolytes in mild and severe preeclampsia: A case‐control study

open access: yesHealth Science Reports, 2023
Background and Aims Magnesium sulfate (MgSO4) treatment is widely used for the prevention of eclamptic seizures. However, its effect on mediators of endothelial dysfunction (ED) and electrolytes remains unclear.
Linda A. Fondjo   +5 more
doaj   +1 more source

Adrenomedullin and Glucocorticoids interaction at the glial/endothelial interface: two sides of the same regulatory coin? [PDF]

open access: yes, 2014
Adrenomedullin is a vasodilatatory peptide, important during the inflammation process and also able to regulate blood-brain barrier function. Adrenomedullin and its receptors have been shown to be glucocorticoid-dependent in many cell types, including ...
Paul, Carolyn, Liverani, E
core   +1 more source

Amylin: Localization, Effects on Cerebral Arteries and on Local Cerebral Blood Flow in the Cat

open access: yesThe Scientific World Journal, 2001
Amylin and adrenomedullin are two peptides structurally related to calcitonin gene-related peptide (CGRP). We studied the occurrence of amylin in trigeminal ganglia and cerebral blood vessels of the cat with immunocytochemistry and evaluated the role of ...
Lars Edvinsson   +2 more
doaj   +1 more source

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