Paradoxical Alopecia Areata Induced by IL‐17 and IL‐23 Inhibitors: A Systematic Review
This systematic review identifies consistent clinical patterns of alopecia areata associated with IL‐17 and IL‐23 inhibitors, most frequently involving secukinumab and ustekinumab. Disease severity varied widely, and management often required biologic discontinuation or therapeutic switching.
Isabella Kamholtz +2 more
wiley +1 more source
Season of birth affects the risk of adult-onset asthma in Finland. [PDF]
Koskinen A +10 more
europepmc +1 more source
Childhood Adversity, Early-Onset Depressive/Anxiety Disorders, and Adult-Onset Asthma
Objectives: To investigate a) whether childhood adversity predicts adult-onset asthma; b) whether early-onset depressive/anxiety disorders predict adult-onset asthma; and c) whether childhood adversity and early-onset depressive/anxiety disorders predict
Kessler, Ronald C. +12 more
core +1 more source
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu +2 more
wiley +1 more source
Identifying risk factors for COPD and adult-onset asthma: an umbrella review. [PDF]
Holtjer JCS +9 more
europepmc +1 more source
Design and Development of Novel Airway Device for Transoral Respiratory Monitoring During Sedation
This article describes iterative design factors and results of clinical testing for a novel medical device that promotes transoral respiratory gas exchange for patients during sedation. A minimally viable prototype was 3D printed from thermoplastic polyurethane and demonstrated high levels of oral retention, gas exchange, and satisfaction among ...
Samuel L. Oyer +7 more
wiley +1 more source
Association of Glucagon‐Like Peptide—1 Receptor Analogues and Laryngeal Symptoms in Obese Adults
Table 1 succinctly quantifies the time‑dependent association between GLP‑1RA/GIP therapy and laryngeal symptoms, demonstrating modest but statistically robust increases in outcomes such as cough and voice/resonance disorders by 6 months. It provides clinically actionable absolute risks, odds ratios, and hazard ratios that can directly inform counseling,
Priyanka Shah +4 more
wiley +1 more source
Comorbidities in childhood-onset and adult-onset asthma. [PDF]
Mendy A, Mersha TB.
europepmc +1 more source
Intraoperative Bradycardia: Evaluating Vasovagal Events in Adult Suspension Microlaryngeal Surgery
This retrospective single‐surgeon cohort study of 190 adults undergoing suspension microlaryngoscopy found that 8.9% (17/190) developed significant intraoperative bradycardia consistent with a vasovagal response (VVR). No demographic, comorbidity, or procedural factors were significantly associated with VVR, though most affected patients required ...
Thomas Q. McClelland +4 more
wiley +1 more source
Factors Associated With Bilateral Involvement in Non‐Infectious Labyrinthitis: A Case–Control Study
Non‐infectious labyrinthitis may progress from unilateral to bilateral inner‐ear involvement, resulting in greater functional impairment. In this retrospective case–control study of 50 patients, younger age, female sex, and the presence of systemic disease were associated with bilateral involvement. These exploratory findings may help identify patients
Douglas Henderson +9 more
wiley +1 more source

