Results 121 to 130 of about 2,492,374 (226)

Association of genetic risk and lifestyle with incident adult-onset asthma in the UK Biobank cohort. [PDF]

ERJ Open Res, 2023
Liang H, Jing D, Zhu Y, Li D, Zhou X, Tu W, Liu H, Pan P, Zhang Y.   +8 more
europepmc   +1 more source

Synthesis of Microbial‐Derived Octadecanoids

Lipids, EarlyView.
C18‐carbon containing dietary polyunsaturated fatty acids (e.g., linoleic acid, α‐linolenic acid, and γ‐linolenic acid) are metabolized by bacteria in the gut into oxygenated lipid mediators termed octadecanoids. To study the biological function of these compounds, we report here the chemical synthesis of multiple octadecanoids.
Johanna Revol‐Cavalier, Katarína Bankóová, Olivier Salamin, Alessandro Quaranta, Juan Du, Mats Hamberg, Craig E. Wheelock   +6 more
wiley   +1 more source

Parental smoke exposure before age 15 years and offspring asthma trajectories from ages 7 to 53 years

ERJ Open Research
Background and objective Paternal passive smoke exposure before 15 years of age was associated with offspring childhood asthma, but its association with asthma beyond childhood had not been investigated. We aimed to investigate such long-term association.
Jiacheng Liu, Jennifer L. Perret, Caroline J. Lodge, Don Vicendese, N. Sabrina Idrose, Gayan Bowatte, Daniel J. Tan, Adrian J. Lowe, Jonathan V. Pham, Bircan Erbas, John W. Holloway, Cecilie Svanes, Michael J. Abramson, E. Haydn Walters, Shyamali C. Dharmage, Dinh S. Bui   +15 more
doaj   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Associations Between Reproductive Factors and the Risk of Adult-Onset Asthma: A Prospective Cohort Study of European Ancestry. [PDF]

J Gen Intern Med, 2023
Liang H, Li D, Zhu Y, Zhou X, Lin F, Jing D, Su X, Pan P, Zhang Y.   +8 more
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Chronic Respiratory Diseases in the 2023‐Defined WHO Western Pacific Region: Burden and Trends From GBD 2023

Med Research, EarlyView.
Chronic respiratory disease burden in the 2023‐defined WHO Western Pacific Region, 1990–2023: Using the Global Burden of Disease 2023 estimates, this study characterized the incidence, prevalence, deaths, and disability‐adjusted life years (DALYs) associated with chronic respiratory diseases (CRDs) in the 37 WHO Western Pacific Region Member States and
Zhang Yue, Yi‐Cheng Fu, Wen Zuo, Li‐Na Wang, Xing‐Xing Suo, Peng Sun, Jin‐Hui Bian, Ming‐Yan Wang   +7 more
wiley   +1 more source

Vitamin D status, sleep patterns, genetic susceptibility, and the risk of incident adult-onset asthma: a large prospective cohort study. [PDF]

Front Nutr, 2023
Chang Q, Zhu Y, Zhou G, Liang H, Li D, Cheng J, Pan P, Zhang Y.   +7 more
europepmc   +1 more source

DNA Repair Pathway Variants Are Enriched in Individuals with Biallelic AAGGG CANVAS and RFC1‐Related Disease

Movement Disorders, EarlyView.
Abstract Background Cerebellar ataxia, neuropathy and vestibular are flexia syndrome (CANVAS) and RFC1‐related disease are most commonly caused by biallelic AAGGG repeat expansions in RFC1. The high population frequency of this expansion compared to the frequency of CANVAS suggests incomplete penetrance.
Xuemin Wang, Liam G. Fearnley, Kayli C. Davies, Penny Snell, Stuart Lee, Victoria E. Jackson, Justin Read, Michael Milton, Ian H. Harding, Martin B. Delatycki, David J. Szmulewicz, Paul J. Lockhart, Melanie Bahlo, Haloom Rafehi   +13 more
wiley   +1 more source

Adult-Onset Asthma Associated With E-Cigarette Use. [PDF]

Cureus, 2021
Roberts J, Chow J, Trivedi K.
europepmc   +1 more source