Results 201 to 210 of about 2,492,374 (226)
Allergy, EarlyView.ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud +14 more
wiley +1 more source
Allergy, EarlyView.Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth +71 more
wiley +1 more source
Pathogenic Airway Bacteria and Local Immune Responses During Early‐Life Asthma‐Like Episodes
Allergy, EarlyView.This study investigates how Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis associate with airway immune responses during early‐life asthma‐like episodes, and compare these responses between children with and without asthma.
Mathilde Bundgaard Svendsen +12 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Allergen immunotherapy (AIT) has been acknowledged as the only disease‐modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study results may vary substantially.
Roy Gerth van Wijk +10 more
wiley +1 more source
Asthma Remission From Childhood to Young Adulthood–A Population‐Based Cohort Study
Allergy, EarlyView.Among 257 participants with asthma at age 8 years, 39% achieved symptom‐based remission by age 24, 29% achieved clinical remission, and 18% achieved complete remission. Male sex increased the likelihood of symptom‐based remission, while food sensitization and overweight/obesity decreased the likelihood.
Lina Broström +6 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe +24 more
wiley +1 more source
Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases
Allergy, EarlyView.ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz +22 more
wiley +1 more source
Allergy, EarlyView.The spectrum of allergic sensitization in mothers and their offspring was characterized at ages 1–5 years at an extract‐ and molecular level in a North American birth cohort. Fel d 1 was the primary sensitizer in mothers, followed by Phl p 1. Perennial allergen sensitization (Der f 1, Der p 1) was rare at age one but rose sharply by age five.
Mary Asumta Anyango Kodydek +14 more
wiley +1 more source
Three phenotypes of adult-onset asthma
Allergy: European Journal of Allergy and Clinical Immunology, 2013 Adult-onset asthma differs from childhood-onset asthma in many respects. It is more heterogeneous, often severe and frequently associated with loss of lung function.
E H Bel, P J Sterk, A Ten Brinke
exaly +2 more sources
Severe adult-onset asthma: A distinct phenotype
Journal of Allergy and Clinical Immunology, 2013 Some patients with adult-onset asthma have severe disease, whereas others have mild transient disease. It is currently unknown whether patients with severe adult-onset asthma represent a distinct clinical phenotype.
Rene Lutter +2 more
exaly +2 more sources