Results 31 to 40 of about 110,453 (370)
Frontiers in Molecular Neuroscience, 2021 Adult hippocampal neurogenesis is a physiological mechanism contributing to hippocampal memory formation. Several studies associated altered hippocampal neurogenesis with aging and Alzheimer's disease (AD).
Domenica Donatella Li Puma +5 more
doaj +1 more source
Molecular Psychiatry, 2021 Daily calorie restriction (CR) and intermittent fasting (IF) enhance longevity and cognition but the effects and mechanisms that differentiate these two paradigms are unknown.
G. Dias +10 more
semanticscholar +1 more source
Tau Protein and Adult Hippocampal Neurogenesis [PDF]
Frontiers in Neuroscience, 2012 Tau protein is a microtubule-associated protein found in the axonal compartment that stabilizes neuronal microtubules under normal physiological conditions. Tau metabolism has attracted much attention because of its role in neurodegenerative disorders called tauopathies, mainly Alzheimer disease.
Almudena eFuster-Matanzo +9 more
openaire +5 more sources
Cells, 2023 Central nervous system infections caused by pathogens crossing the blood–brain barrier are extremely damaging and trigger cellular alterations and neuroinflammation.
Katerina Segklia +2 more
doaj +1 more source
Long-term exposure to a hypomagnetic field attenuates adult hippocampal neurogenesis and cognition
Nature Communications, 2021 Adult hippocampal neurogenesis contributes to learning and memory, and is sensitive to a variety of environmental stimuli. Exposure to a hypomagnetic field (HMF) influences the cognitive processes of various animals, from insects to human beings. However,
Bingfang Zhang +6 more
semanticscholar +1 more source
Mediator Med23 Regulates Adult Hippocampal Neurogenesis [PDF]
Frontiers in Cell and Developmental Biology, 2020 Mammalian Mediator (Med) is a key regulator of gene expression by linking transcription factors to RNA polymerase II (Pol II) transcription machineries. The Mediator subunit 23 (Med23) is a member of the conserved Med protein complex and plays essential roles in diverse biological processes including adipogenesis, carcinogenesis, osteoblast ...
Guo-Yan Chen +12 more
openaire +3 more sources
Adult neurogenesis, mental health, and mental illness: hope or hype? [PDF]
, 2008 Psychiatric and neurologic disorders take an enormous toll on society. Alleviating the devastating symptoms and consequences of neuropsychiatric disorders such as addiction, depression, epilepsy, and schizophrenia is a main force driving clinical and ...
Cameron, H. A. +5 more
core +1 more source
Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]
, 2020 Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
core +1 more source
Frontiers in Neuroscience, 2018 Streptozotocin (STZ)-induced diabetes impairs learning and memory performance and reduces adult hippocampal neurogenesis. Physical exercise brings beneficial effects.
Suk-Yu Yau +8 more
doaj +1 more source
Adult Neurogenesis Conserves Hippocampal Memory Capacity [PDF]
The Journal of Neuroscience, 2018 The hippocampus is crucial for declarative memories in humans and encodes episodic and spatial memories in animals. Memory coding strengthens synaptic efficacy via an LTP-like mechanism. Given that animals store memories of everyday experiences, the hippocampal circuit must have a mechanism that prevents saturation of overall synaptic weight for the ...
Md Jahangir Alam +5 more
openaire +2 more sources