Results 141 to 150 of about 83,360 (210)
Noninvasive Brain Stimulation Protects Cognitive Impairment in i.c.v. STZ-Injected Rats: Role of Adult Neurogenesis. [PDF]
Kumar A +5 more
europepmc +1 more source
Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
Exploring Interactive Effects of Arsenic and Selenium Exposure on Larval Zebrafish (Danio rerio)
ABSTRACT Arsenic contamination in aquatic ecosystems is a major environmental concern. Selenium (Se) helps mitigate oxidative stress and hence could reduce the toxic effects of arsenic. However, Se can also be toxic at high concentrations. Given that these metalloids commonly co‐occur in the environment, there is a pressing need for further research ...
Owen Luo +6 more
wiley +1 more source
Renin-angiotensin system as an emerging target to modulate adult neurogenesis in health and disease. [PDF]
Rodríguez-Pallares J +3 more
europepmc +1 more source
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco +6 more
wiley +1 more source
Environmentally Realistic Metal Mixture Concentration Impacts Early Development in Zebrafish Larvae
ABSTRACT The dispersion of metals in the environment leads to the presence of metal mixtures in impacted ecosystems, but few studies have addressed their impact on early developmental processes in fish. Here, we investigated the effect of metal mixtures reported in the Doce River basin in Brazil, including Fe, Mn, and Cd, either singly or as a mixture ...
Anderson K. S. Macêdo +4 more
wiley +1 more source
Reduced Adult Neurogenesis in Humans Results From a Tradeoff Rather Than Direct Negative Selection. [PDF]
Morizet D, Bally-Cuif L.
europepmc +1 more source
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho +7 more
wiley +1 more source
Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain. [PDF]
Zhilina D +12 more
europepmc +1 more source
ABSTRACT Endocrine‐disrupting chemicals (EDCs), such as 17α‐ethinylestradiol (EE2), have raised concerns about their potential effects on aquatic organisms, particularly during early developmental stages. In this context, the study of behavioral disruption has gained considerable attention, as it may have consequences on individual fitness and ...
Soloperto Sofia +6 more
wiley +1 more source

