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Switching of RNA splicing regulators in immature neuroblasts during adult neurogenesis. [PDF]
ElifeBernou C +12 more
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Natural variations of adult neurogenesis and anxiety predict hierarchical status of inbred mice
Grieco F, Balla A, Larrieu T, Toni N.
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NeuroReport, 1996 This report describes neurogenesis in the adult human olfactory epithelium in vitro. Olfactory epithelium was collected at autopsy and by biopsy, and grown in serum-free medium. Basic fibroblast growth factor induced the differentiation of bipolar cells which were immunopositive for several neuronal proteins but not glial proteins.
Murrell, Wayne +6 more
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A fresh look at adult neurogenesis
Nature Medicine, 2019Improved protocols for the visualization of immature neurons in the human brain provide evidence for generation of neurons in the adult hippocampus and uncover reduced neurogenesis in Alzheimer’s disease.
Jonas Frisen
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An Overview of Adult Neurogenesis
2021Neurogenesis is maintained in the mammalian brain throughout adulthood in two main regions: the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the hippocampal dentate gyrus. Adult neurogenesis is a process composed of multiple steps by which neurons are generated from dividing adult neural stem cells and migrate ...
Ribeiro, Filipa F., Xapelli, Sara
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Perspectives on adult neurogenesis
European Journal of Neuroscience, 2011New neurons are generated throughout life. This discovery has challenged firmly held concepts about the structural plasticity and regenerative capacity of the mammalian brain. In this special issue of the EJN, leaders in the field summarize and review recent advances aiming to understand the molecular mechanisms underlying adult neurogenesis and the ...
Knobloch Marlen, Jessberger Sebastian
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Neurogenesis in the adult hippocampus
Hippocampus, 2006AbstractThe dentate gyrus (DG) contains one of the few neuronal populations in the mammalian brain that are generated throughout life. Research into the regulation and function of adult neurogenesis continues its rapid growth in popularity. With the researcher new to the field in mind, we review the processes that together constitute adult neurogenesis
Brian R, Christie, Heather A, Cameron
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Signaling in Adult Neurogenesis
Annual Review of Cell and Developmental Biology, 2009The identification of neural stem cells (NSCs) and their contribution to continuous neurogenesis has shown that the hippocampus and olfactory bulb are plastic. Brain plasticity, achieved at the level of cell genesis, has an essential role in the maintenance of brain homeostasis.
Hoonkyo, Suh, Wei, Deng, Fred H, Gage
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Hippocampus, 2006
AbstractStress hormones have potent growth‐inhibiting effects on a variety of peripheral tissues. Consistent with this general function, stress has been shown to inhibit cell proliferation and, ultimately, neurogenesis in the hippocampus. This effect appears to be common across mammalian species, life stages, and most types of stressors.
Christian, Mirescu, Elizabeth, Gould
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AbstractStress hormones have potent growth‐inhibiting effects on a variety of peripheral tissues. Consistent with this general function, stress has been shown to inhibit cell proliferation and, ultimately, neurogenesis in the hippocampus. This effect appears to be common across mammalian species, life stages, and most types of stressors.
Christian, Mirescu, Elizabeth, Gould
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Neurogenesis in the adult hippocampus
Cell and Tissue Research, 2007New neurons continue to be generated in two privileged areas of the adult brain: the dentate gyrus of the hippocampal formation and the olfactory bulb. Adult neurogenesis has been found in all mammals studied to date, including humans. The process of adult neurogenesis encompasses the proliferation of resident neural stem and progenitor cells and their
Dan, Ehninger, Gerd, Kempermann
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