Results 11 to 20 of about 49,140 (359)
Journal of Diabetes Investigation, 2021 The high plasma glucose induced in glucose metabolism disorders leads to the non‐enzymatic glucose‐dependent modification (glycation) of type 1 collagen, which is an essential component of bone tissue.
Kei‐ichiro Kitamura +6 more
doaj +1 more source
Humoral factors in the formation of neuroosteoarthropathy in type 2 diabetes mellitus
Сахарный диабет, 2023 BACKGROUND: Diabetic neuroosteoarthropathy is a severe and insufficiently studied complication of diabetes mellitus, which is characterized by progressive destruction of bones and joints against the background of neuropathy and leads to the formation of ...
M. M. Kalandiya +5 more
doaj +1 more source
Advanced Glycation End Products and Psoriasis
Vaccines, 2023 Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins. They accumulate slowly in tissues during ageing but also in metabolic and selected inflammatory disorders.
Martina Maurelli +2 more
openaire +4 more sources
Advanced glycation end-products: a review [PDF]
Diabetologia, 2001 Advanced glycation end-products are a complex and heterogeneous group of compounds that have been implicated in diabetes related complications. At present it is not known if they are the cause or the consequence of the complications observed. We discuss the chemistry of advanced glycated end-product formation and their patho-biochemistry particularly ...
R, Singh, A, Barden, T, Mori, L, Beilin
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Prevention of Protein Glycation by Natural Compounds [PDF]
, 2015 Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz +1 more
core +5 more sources
Zinc against advanced glycation end products [PDF]
Clinical and Experimental Pharmacology and Physiology, 2018 SummaryAdvanced glycation end products (AGEs) are destructive compounds with pathogenic importance in age‐related chronic diseases. Zinc has antioxidant, anti‐inflammatory and anti‐apoptotic potential. This study aimed to summarize effects of zinc onAGEformation andAGE‐induced damaging agents.
Sorayya Kheirouri +2 more
openaire +2 more sources
Egyptian Journal of Medical Human Genetics, 2022 Background Hashimoto's thyroiditis is the most widespread autoimmune illness targeting a specific organ. "Redox homeostasis" is achieved when the production of Reactive Oxygen Species and their elimination are in balance. Advanced glycation end products (
Noura Mostafa Mohamed +1 more
doaj +1 more source
Antioxidants, 2021 The glyoxal-lysine dimer (GOLD), which is a glyoxal (GO)-derived advanced glycation end product (AGE), is produced by the glycation reaction. In this study, we evaluated the effect of GOLD on the oxidative damage and inflammatory response in SV40 MES 13 ...
Hee-Weon Lee +6 more
doaj +1 more source
Advanced glycation end products [PDF]
Dermato-Endocrinology, 2012 Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed.
Gkogkolou, Paraskevi, Böhm, Markus
openaire +2 more sources
Association between plasma sRAGE and emphysema according to the genotypes of AGER gene
BMC Pulmonary Medicine, 2022 Background Higher soluble receptor for advanced glycation end product (sRAGE) levels are considered to be associated with severe emphysema. However, the relationship remains uncertain when the advanced glycation end-product specific receptor (AGER) gene ...
Sooim Sin +4 more
doaj +1 more source