Results 11 to 20 of about 37,721 (216)

The Role of Advanced Glycation End Products on Dyslipidemia [PDF]

Metabolites, 2023
Disorders of lipoprotein metabolism and glucose homeostasis are common consequences of insulin resistance and usually co-segregate in patients with metabolic syndrome and type 2 diabetes mellitus (DM). Insulin-resistant subjects are characterized by atherogenic dyslipidemia, a specific lipid pattern which includes hypertriglyceridemia, reduced high ...
Jelena Vekic, Sanja Vujcic, Biljana Bufan, Dragana Bojanin, Khamis Al-Hashmi, Khaild Al-Rasadi, Anca Pantea Stoian, Aleksandra Zeljkovic, Manfredi Rizzo   +8 more
openaire   +5 more sources

Predictive ability of serum advanced glycation end products at 11 to 13 weeks of gestation for early-onset preeclampsiaAJOG Global Reports at a Glance

AJOG Global Reports, 2022
BACKGROUND: Placental hypoxia and resultant oxidative stress have been associated with the development of preeclampsia. Oxidative stress promotes the formation of advanced glycation end products. OBJECTIVE: This study aimed to assess whether serum levels
Minako Goto, MD, Sho-ichi Yamagishi, MD, Takanori Matsui, PhD, Keiko Koide, MD, Hiroko Takita, MD, Mayumi Tokunaka, MD, Akihiko Sekizawa, MD   +6 more
doaj   +1 more source

Improved Arterial Compliance by a Novel Advanced Glycation End-Product Crosslink Breaker [PDF]

Circulation, 2001
David A. Kass, Edward P. Shapiro, Miho Kawaguchi, Anne Capriotti, Angelo Scuteri, Robert C. deGroof, Edward G. Lakatta   +6 more
openalex   +2 more sources

Biophysical Characterisation of Amadori Modified Human Serum Albumin: A Prognostic Biomarker for Diabetic Complications [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Glycation of biological macromolecules particularly protein leads to the generation of early and Advanced Glycation End (AGE) products. The interest in early glycation of protein is driven due to the fact of Amadori modified proteins having
Binish Arif, Zubair Ahmad, Gulzar Ahmad Bhat, Syed Mudassar, Khursheed Aalam   +4 more
doaj   +1 more source

Advanced Glycation End Products and Psoriasis

Vaccines, 2023
Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins. They accumulate slowly in tissues during ageing but also in metabolic and selected inflammatory disorders.
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni   +2 more
openaire   +4 more sources

Advanced glycation end products and cognitive impairment in schizophrenia.

PLoS ONE, 2021
Advanced glycation end products play a key role in the pathophysiology of schizophrenia. Cognitive impairment is one of the central features of schizophrenia; however, the association between advanced glycation end products and cognitive impairment ...
Akiko Kobori, Mitsuhiro Miyashita, Yasuhiro Miyano, Kazuhiro Suzuki, Kazuya Toriumi, Kazuhiro Niizato, Kenichi Oshima, Atsushi Imai, Yukihiro Nagase, Akane Yoshikawa, Yasue Horiuchi, Syudo Yamasaki, Atsushi Nishida, Satoshi Usami, Shunya Takizawa, Masanari Itokawa, Heii Arai, Makoto Arai   +17 more
doaj   +1 more source

A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer. [PDF]

PLoS ONE, 2018
Advanced glycation end products are formed by non-enzymatic reactions between proteins and carbohydrates, causing irreversible lysine and arginine alterations that severely affect protein structure and function.
Ulrika Wendel, Nina Persson, Christian Risinger, Eva Bengtsson, Björn Nodin, Lena Danielsson, Charlotte Welinder, Gunilla Nordin Fredrikson, Bo Jansson, Ola Blixt   +9 more
doaj   +1 more source

Glyoxal‐induced formation of advanced glycation end‐products in type 1 collagen decreases both its strength and flexibility in vitro

Journal of Diabetes Investigation, 2021
The high plasma glucose induced in glucose metabolism disorders leads to the non‐enzymatic glucose‐dependent modification (glycation) of type 1 collagen, which is an essential component of bone tissue.
Kei‐ichiro Kitamura, Jun Hirayama, Yoshiaki Tabuchi, Takao Minami, Hajime Matsubara, Atsuhiko Hattori, Nobuo Suzuki   +6 more
doaj   +1 more source

Humoral factors in the formation of neuroosteoarthropathy in type 2 diabetes mellitus

Сахарный диабет, 2023
BACKGROUND: Diabetic neuroosteoarthropathy is a severe and insufficiently studied complication of diabetes mellitus, which is characterized by progressive destruction of bones and joints against the background of neuropathy and leads to the formation of ...
M. M. Kalandiya, E. A. Kogan, L. V. Nikankina, A. Y. Tokmakova, E. L. Zaitseva, G. R. Galstyan   +5 more
doaj   +1 more source

Fingertip-Measured Skin Carotenoids and Advanced Glycation End Product Levels in Glaucoma

Antioxidants, 2022
Carotenoids have antioxidant properties, and the accumulation of advanced glycation end products (AGEs) is associated with reactive oxygen species production; they have attracted attention as factors predictive of the onset and progression in glaucoma ...
Yoichi Kadoh, Yuji Takayanagi, Junichi Sasaki, Masaki Tanito   +3 more
doaj   +1 more source