Pooled data from randomised controlled trials demonstrate that supplementation with curcumin or turmeric leads to a significant reduction in systolic blood pressure (SBP) in individuals with prediabetes and type 2 diabetes. While the overall effect on diastolic blood pressure (DBP) was not significant, a pre‐specified subgroup analysis showed a ...
Hossein Bahari +5 more
wiley +1 more source
Advanced glycation end product-modified low-density lipoprotein promotes pro-osteogenic reprogramming via RAGE/NF-κB pathway and exaggerates aortic valve calcification in hamsters. [PDF]
Yang X +12 more
europepmc +1 more source
Circular RNAs as Biomarkers and Therapeutic Targets in Diabetic Cardiovascular Complications
This graphic abstract elaborates on the recent mechanism of circular RNAs (circRNAs) in the pathogenesis, diagnosis and treatment of diabetic cardiovascular complications. Diabetes mellitus induces oxidative/inflammatory stress, followed by endothelial dysfunction and leads to micro‐/macro‐vascular complications.
Shreya Singh Beniwal +10 more
wiley +1 more source
This figure summarises circRNAs identified as therapeutic or pathogenic targets in animal models of diabetic foot ulcers. Protective circRNAs delivered via exosomes, hypoxia‐preconditioned exosomes, or lipid nanoparticles promote angiogenesis, autophagy, and oxidative stress resistance. In contrast, silencing of pathogenic circRNAs such as circ_0005654
Amir Reza Ghafourian +6 more
wiley +1 more source
Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)
ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley +1 more source
Fried potato consumption is increasingly associated with metabolic disorders, yet preventive strategies remain poorly understood. In a 13‐week mouse model, long‐term potato chip intake induced significant glycolipid metabolic disturbances and tissue damage, which were ameliorated by fish oil supplementation through modulation of inflammation, hepatic ...
Xuzhi Wan +10 more
wiley +1 more source
Quercetin ameliorates advanced glycation end product-induced wound healing impairment and inflammaging in human gingival fibroblasts. [PDF]
Huang CY +7 more
europepmc +1 more source
L‐theanine alleviates alcohol exposure‐induced kidney injury through a multiple mechanisms. ABSTRACT Alcohol exposure induces kidney oxidative stress and inflammatory responses. L‐theanine (LTA) can protect the kidneys through its antioxidant and immunomodulatory effects; however, its role and underlying mechanisms in alleviating alcoholic kidney ...
Xuhui Dang +6 more
wiley +1 more source
DNA Aptamer Raised against Advanced Glycation End Products Improves Sperm Concentration, Motility, and Viability by Suppressing Receptors for Advanced Glycation End Product-Induced Oxidative Stress and Inflammation in the Testes of Diabetic Mice. [PDF]
Mori Y +10 more
europepmc +1 more source

