Results 31 to 40 of about 37,721 (216)

Advanced Glycation End Products, Soluble Receptor for Advanced Glycation End Products, and Risk of Colorectal Cancer [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2011
Abstract Background: Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE–ligand engagement ...
Stephanie J. Weinstein, Philip R. Taylor, Jarmo Virtamo, Barry I. Graubard, Demetrius Albanes, Li Jiao, Rachael Z. Stolzenberg-Solomon   +6 more
openaire   +3 more sources

Advanced Glycation End Products in Health and Disease

Microorganisms, 2022
Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed by further glycoxidation reactions under oxidative stress conditions, are involved in the onset and exacerbation of a variety of diseases, including diabetes, atherosclerosis ...
V. Prakash Reddy, Puspa Aryal, Emmanuel K. Darkwah   +2 more
openaire   +3 more sources

A novel crosslinked type of advanced glycation end-product derived from lactaldehyde

Heliyon, 2020
Glycation of amino or guanidino groups of proteins with glucose and glucose-derived reactive aldehydes, such as α-hydroxyaldehydes, leads to accumulation of advanced glycation end-products (AGEs) in the body, resulting in diabetic complications and age ...
Tomoaki Shigeta, Kazumi Sasamoto, Tetsuro Yamamoto   +2 more
doaj   +1 more source

Extrusion of lupines with or without addition of reducing sugars: Effects on the formation of Maillard reaction compounds, partition of nitrogen and Nε-carboxymethyl-lysine, and performance of dairy cows

Journal of Dairy Science, 2023
: The extrusion of leguminous seeds induces the formation of Maillard reaction compounds (MRC) as a product of protein advanced glycation and oxidation, which lowers protein degradability in the rumen.
E. Manzocchi, A. Ferlay, S. Mendowski, G. Chesneau, P. Chapoutot, S. Lemosquet, G. Cantalapiedra-Hijar, P. Nozière   +7 more
doaj   +1 more source

Advanced Glycation End Products and Receptor for Advanced Glycation End Products in AA Amyloidosis

The American Journal of Pathology, 2003
Advanced glycation end products (AGEs) may be involved in either amyloidogenesis or complications related to amyloid. We hypothesized that AGEs may influence the pathogenesis of AA amyloidosis, and investigated the spatial and temporal relationship between AGEs, carboxy methyl lysine (CML), the AGE receptor (RAGE), and AA amyloid in humans and mice ...
Sophie Mansfeld, B. Stix, Christoph Röcken, Frank Bühling, Kay Stubenrauch, Bernd Weigle, Mona Schwan, Wolfgang Saeger, Rosemarie Kientsch-Engel   +8 more
openaire   +3 more sources

Inhibition of Advanced Glycation End-Product Formation by High Antioxidant-Leveled Spices Commonly Used in European Cuisine

Antioxidants, 2019
Spices and herbs, as good sources of polyphenols, could be strong inhibitors of advanced glycation end-product (AGE) formation. The aim of this research was to measure the ability of various spices to inhibit AGEs and to study the correlation of AGE ...
Małgorzata Starowicz, H. Zieliński
semanticscholar   +1 more source

Advanced Glycation End Products and Diabetic Complications [PDF]

The Korean Journal of Physiology & Pharmacology, 2014
During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation. Protein glycation and formation of advanced glycation end products (AGEs) play an important role in the pathogenesis of diabetic complications like retinopathy, nephropathy ...
Varun Parkash Singh, Nirmal Singh, Anjana Bali, Amteshwar Singh Jaggi   +3 more
openaire   +3 more sources

Ginseng improves cognitive deficit via the RAGE/NF-κB pathway in advanced glycation end product-induced rats

Journal of Ginseng Research, 2015
Background: Ginseng, the root of Panax ginseng (PG), is used widely as a herbal medicine to prevent and treat various diseases. Panax ginseng has pharmacological effects on neurodegenerative diseases such as Alzheimer's disease (AD).
Xiaobin Tan, Junfei Gu, Bingjie Zhao, Shuyuan Wang, Jiarui Yuan, Chunfei Wang, Juan Chen, Jiping Liu, Liang Feng, Xiaobin Jia   +9 more
doaj   +1 more source

Dietary Advanced Glycation End Products and Aging [PDF]

Nutrients, 2010
Advanced glycation end products (AGEs) are a heterogeneous, complex group of compounds that are formed when reducing sugar reacts in a non-enzymatic way with amino acids in proteins and other macromolecules. This occurs both exogenously (in food) and endogenously (in humans) with greater concentrations found in older adults.
Karen Chapman-Novakofski, Claudia Luevano-Contreras   +1 more
openaire   +3 more sources

Pathological Implications of Receptor for Advanced Glycation End-Product (AGER) Gene Polymorphism

Disease Markers, 2019
The receptor for advanced glycation end-products (RAGE) is a cell surface transmembrane multiligand receptor, encoded by the AGER gene. RAGE presents many transcripts, is expressed mainly in the lung, and involves multiple pathways (such as NFκB, Akt ...
Marine Serveaux-Dancer, M. Jabaudon, I. Creveaux, C. Belville, R. Blondonnet, Christelle Gross, J. Constantin, L. Blanchon, V. Sapin   +8 more
semanticscholar   +1 more source