Effect of diabetes and aminoguanidine therapy on renal advanced glycation end-product binding [PDF]
, 1999 Sherif Youssef +5 more
openalex +1 more source
PROTEOMICS – Clinical Applications, EarlyView.ABSTRACT Proteomic analysis of biofluids is central for identifying disease biomarkers. Tears have become popular targets for biomarker discovery and biosensor development, largely because they can be collected noninvasively and are rich sources of biomarkers for ocular and systemic diseases. Although basal and reflex tears have been well characterized,
Campbell Bruce Mousseau +3 more
wiley +1 more source
The effect of advanced glycation endproduct accumulation on bone [PDF]
, 2017 Diabetes is associated with increased fracture risk, which leads to increased morbidity and eventual mortality with a substantial financial burden.
Van Vliet, Miranda
core
Role of the Janus kinase (JAK)/signal transducters and activators of transcription (STAT) cascade in advanced glycation end-product-induced cellular mitogenesis in NRK-49F cells [PDF]
, 1999 Jau‐Shyang Huang +6 more
openalex +1 more source
Nrf2‐Mediated Ferroptosis Is Involved in Berberine‐Induced Alleviation of Diabetic Kidney Disease
Phytotherapy Research, EarlyView.ABSTRACT Diabetic kidney disease (DKD) is the most common and serious complication of diabetes mellitus. Currently, there is a lack of safe and effective preventive strategies for DKD. The study aimed to explore the preventive effects and potential mechanisms of berberine (BBR) against DKD.
Kun Gao +6 more
wiley +1 more source
Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases
Small Science, EarlyView.This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li +7 more
wiley +1 more source
Epitopes close to the apolipoprotein B low density lipoprotein receptor-binding site are modified by advanced glycation end products [PDF]
, 1998 Xingyu Wang +2 more
openalex +1 more source
Aging Cell, EarlyView.We developed a human microglia aging model by doxycycline‐induced GFP‐progerin expression, which offers a valuable tool to study human microglial aging and its contribution to neurodegeneration. Induced HMC3‐Progerin cells exhibited increased age markers as well as transcriptomic alterations, including an age‐associated transcriptomic shift and ...
Christiane Hartmann +16 more
wiley +1 more source
Frontiers in MedicineDiabetes is a global health problem, with diabetic wounds constituting one of its most severe complications. Advanced glycation end products (AGEs) and their receptor, the receptor for advanced glycation end products (RAGE), play a key role in the ...
Haohui Lin +7 more
doaj +1 more source
Assessment of Oral Glycine and Lysine Therapy on Receptor for Advanced Glycation End Products and Transforming Growth Factor Beta Expression in the Kidney of Streptozotocin-Induced Diabetic Rats in Comparison with Normal Rats [PDF]
Journal of Kerman University of Medical Sciences, 2014 Background & Aims: Today, diabetic nephropathy is considered to be one of the most common causes of end stage renal disease. Uncontrolled hyperglycemia, and consequently, production of advanced glycation end products activate pathways which play key ...
Somayeh Sadat Heidary +3 more
doaj