Results 131 to 140 of about 8,200,615 (297)

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Biomarkers of Pre‐COPD Lung Function Trajectories in Middle Age: A Prospective Study From 1st to 6th Decade

Respirology, EarlyView.
Identifying impaired lifetime lung function trajectories is key to identifying the preclinical phase of COPD (Pre‐COPD) or prognosis of COPD. We have identified that some circulating established COPD biomarkers differ across ‘pre‐COPD’ lung function trajectories, suggesting that some COPD‐specific pathobiological processes, including inflammation, are ...
Dinh S. Bui, Don Vicendese, Jonathan Pham, Nur Sabrina Idrose, Adrian Lowe, Caroline Lodge, Raisa Cassim, Chamara Senaratna, Gayan Bowatte, Garun Hamilton, Alan James, Paul Thomas, Richard Wood‐Baker, Peter Frith, Gary Anderson, Philip M. Hansbro, Graeme Zosky, George Washko, Michael J. Abramson, Rosa Faner, Alvar Agusti, Jennifer Perret, E. Haydn Walters, Shyamali C. Dharmage   +23 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Association between Moraxella keratitis and advanced glycation end products

Scientific Reports
Diabetes mellitus is recognized as a major predisposing factor for Moraxella keratitis. However, how diabetes mellitus contributes to Moraxella keratitis remains unclear.
Hidenori Inoue, Koji Toriyama, Naoko Takahira, Shinobu Murakami, Hitoshi Miyamoto, Takashi Suzuki, Atsushi Shiraishi   +6 more
doaj   +1 more source

Glycation at the Crossroads of Disease Pathogenesis: Mechanistic Insights and Therapeutic Frontiers

Diseases
Protein glycation is a nonenzymatic modification that links sugar chemistry to molecular aging and chronic disease. Sequential reactions involving Schiff bases, Amadori products, and reactive α dicarbonyl intermediates generate advanced glycation end ...
Sneha Krishnamoorthi, Rupachandra Saravanakumar, Vivek Kumar   +2 more
doaj   +1 more source

Determination of Advanced Glycation End Products Intake Levels in University Students

, 2021
ÖZ Amaç: Çalışmanın amacı, üniversite öğrencilerinin ileri glikasyon son ürünleri alım seviyelerinin belirlenmesidir. Gereç ve Yöntem: Çalışma 2018 yılı Mayıs-Temmuz ayları arasında İstanbul Sabahattin Zaim Üniversitesinde okuyan, 200 öğrenci üzerinde ...

core  

Immunomodulatory Nanozymes as Programmable Redox–Immune Set‐Point Regulators

Small, EarlyView.
Conceptual phase space linking reactive oxygen species level/dynamics to immune state, with pathological set‐points for chronic inflammation, tumor escape, and degeneration contrasted against a central healthy redox–immune set‐point. Buffering and amplifying nanozymes are depicted as devices that dial redox tone up or down to steer diseased ...
Sumi Choi, Minjeong Kim, Sang Jin Lee, Su‐Hwan Kim   +3 more
wiley   +1 more source

The natural history of periodontal disease—Part 2: In populations with access to dental care: The Studies of Health in Pomerania (SHIP)

Periodontology 2000, EarlyView., 2023
Abstract In this descriptive analysis of the 21‐year follow‐up data from the SHIP‐START cohort and the 7‐year follow‐up data from the SHIP‐TREND cohort, we report the progression of clinical attachment levels (CAL), age effects on CAL change, and a detailed description of CAL progression and remission. At baseline, 4307 and 4420 persons participated in
Thomas Kocher, Peter Meisel, Reiner Biffar, Henry Völzke, Birte Holtfreter   +4 more
wiley   +1 more source

Targeting the AGEs-RAGE axis: pathogenic mechanisms and therapeutic interventions in diabetic wound healing

Frontiers in Medicine
Diabetes is a global health problem, with diabetic wounds constituting one of its most severe complications. Advanced glycation end products (AGEs) and their receptor, the receptor for advanced glycation end products (RAGE), play a key role in the ...
Haohui Lin, Yi Yang, Xia Wang, Manhon Chung, Li Zhang, Sa Cai, Xiaohua Pan, Yu Pan   +7 more
doaj   +1 more source