Results 291 to 300 of about 94,238 (337)
Some of the next articles are maybe not open access.
Advanced Glycation End Products
2020Advanced glycation end products (AGEs) play a major role in diabetic vascular complications, such as chronic kidney disease (CKD), by activating pro-oxidant and pro-inflammatory responses. Although traditionally AGEs have been associated with uncontrolled hyperglycemia of diabetes mellitus, there is increasing evidence that exogenous AGEs from diet ...
Annabel Biruete, Jaime Uribarri
openaire +1 more source
Methods to assess advanced glycation end-products
Current Opinion in Clinical Nutrition & Metabolic Care, 2021Purpose of review Advanced glycation end-products (AGEs) resulting from protein glycoxidation constitute biomarkers of interest in different pathological situations. Several methods for quantifying AGEs in biological fluids or tissues have been developed without any real consensus on a gold standard method.
Stéphane, Jaisson, Philippe, Gillery
openaire +2 more sources
Advanced glycation end products: A nephrologist's perspective
American Journal of Kidney Diseases, 2000Advanced glycation end products (AGEs) are a heterogeneous group of molecules that accumulate in plasma and tissues with advancing age, diabetes, and renal failure. There is emerging evidence that AGEs are potential uremic toxins and may have a role in the pathogenesis of vascular and renal complications associated with diabetes and aging.
D S, Raj +3 more
openaire +2 more sources
Advanced Glycation End Products and Diabetic Retinopathy
Current Medicinal Chemistry, 2013Diabetic retinopathy (DR) has a complex pathogenesis which is impacted by a raft of systemic abnormalities and tissue-specific alterations occurring in response to the diabetes milieu. Many pathogenic processes play key roles in retinal damage in diabetic patients.
Chen, M., Curtis, T. M., Stitt, A. W.
openaire +3 more sources
Advanced glycation end products, diabetes and ageing
Zeitschrift für Gerontologie und Geriatrie, 2007Advanced glycation end products (AGEs) are formed in vivo by a non-enzymatic reaction of proteins with carbohydrates and accumulate in many tissues during ageing. They are discussed as being responsible for many age- and diabetes-related diseases. On the other hand, AGEs are formed by the heating of food and are taken up by the nutrition.
N, Nass +6 more
openaire +2 more sources
Advanced Glycation End Products
2011Prolonged hyperglycemia, dyslipidemia and oxidative stress in diabetes result in the increased production and accumulation of advanced glycation end products (AGEs) in the kidney. Covalent AGE modifications significantly influence the structure and function of key protein targets.
openaire +2 more sources
Advanced Glycation End Products (AGEs)
2019Glycation refers to the addition of a sugar moiety to a protein molecule and occurs during the Maillard reaction. Maillard reaction is initiated by the condensation of amino groups of proteins, peptides, and amino acids with carbonyl groups of reducing sugars.
Akıllıoğlu, Halise Gül +1 more
openaire +2 more sources
Advanced glycation end products strongly activate platelets
European Journal of Nutrition, 2009Diabetes mellitus is characterized by hyperglycemia that plays an important role in the pathogenesis of diabetic complications including cardiovascular diseases. Moreover, hyperglycemia induces increased generation of advanced glycation end products (AGEs).
Thomas, Gawlowski +8 more
openaire +2 more sources
Advanced glycation end products and diabetic retinopathy
Amino Acids, 2011Retinopathy is a serious microvascular complication of diabetes and a major cause of blindness in young adults, worldwide. Early diabetic retinopathy is characterized by a loss of pericytes from retinal capillaries, the appearance of acellular capillaries and microaneurysms, and a breakdown of the blood-retinal barrier. In later stages, this can evolve
Ross, Milne, Seymour, Brownstein
openaire +2 more sources
Advanced glycation end-products and peritoneal sclerosis
Seminars in Nephrology, 2004Long-term continuous ambulatory peritoneal dialysis (CAPD) often causes peritoneal fibrosis and sclerosis with a loss of function, and some CAPD patients develop sclerosing encapsulating peritonitis. Glucose-based peritoneal dialysis fluids readily produce glucose degradation products by heat sterilization, and glucose degradation products accelerate ...
Sakurako, Nakamura, Toshimitsu, Niwa
openaire +2 more sources