Results 71 to 80 of about 94,238 (337)

Research Progress on Natural Products Inhibiting Advanced Glycation End Products [PDF]

Shipin Kexue
Glycation is the non-enzymatic reaction between sugars (glucose and fructose) and proteins or lipids, giving rise to the formation of advanced glycation end products (AGEs).
QI Yawei, LIU Haochi, LIU Jifeng
doaj   +1 more source

Advanced Glycation End Products Evolution after Pancreas-Kidney Transplantation: Plasmatic and Cutaneous Assessments [PDF]

, 2016
Diabetes mellitus leads to increased Advanced Glycation End Products (AGE) production, which has been associated with secondary diabetic complications. Type 1 diabetic patients undergoing pancreas-kidney transplantation (SPKT) can restore normoglycemia ...
Castro-Henriques, A., Fonseca, R., Gouveia, C., Martins, L., Noronha, I., Oliveira, J., Rodrigues, A., Silva, D., Vizcaíno, J.   +8 more
core   +1 more source

Dietary Advanced Glycation End Products and Aging [PDF]

Nutrients, 2010
Advanced glycation end products (AGEs) are a heterogeneous, complex group of compounds that are formed when reducing sugar reacts in a non-enzymatic way with amino acids in proteins and other macromolecules. This occurs both exogenously (in food) and endogenously (in humans) with greater concentrations found in older adults.
Luevano-Contreras, Claudia, Chapman-Novakofski, Karen   +1 more
openaire   +2 more sources

A Quantum Framework for Protein Binding‐Site Structure Prediction on Utility‐Level Quantum Processors

Advanced Science, EarlyView.
This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang, Yuxin Yang, William Martin, Kingsten Lin, Zixu Wang, Cheng‐Chang Lu, Weiwen Jiang, Ruth Nussinov, Joseph Loscalzo, Qiang Guan, Feixiong Cheng   +10 more
wiley   +1 more source

Osseous wound repair under inhibition of the axis of advanced glycation end-products and the advanced glycation end-products receptor

Journal of the Formosan Medical Association, 2015
Blockade of advanced glycation end-products (AGE) is able to reduce diabetic complications and control periodontitis. This study aimed to determine whether the application of aminoguanidine (AG), an AGE inhibitor, or N-phenacylthiazolium bromide (PTB ...
Sheng-Chueh Tsai, Yi-Han Jheng, Chen-Ying Wang, Yi-Wen Chen, Yu-Fang Lin, Chih-Cheng Chen, Po-Chun Chang   +6 more
doaj   +1 more source

Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells [PDF]

, 2013
Background: Advanced glycation end products (AGEs), the final products of the Maillard reaction, have been shown to impair endothelial proliferation and function, thus contributing to endothelial cell injury present in diabetes, inflammatory and ...
Adamopoulos, Christos, Farmaki, Elena, Kiaris, Hippokratis, Papavassiliou, Athanasios G., Piperi, Christina, Spilioti, Eliana   +5 more
core   +1 more source

Advanced glycation end‐products and the kidney [PDF]

European Journal of Clinical Investigation, 2010
Eur J Clin Invest 2010; 40 (8): 742–755AbstractBackground Advanced glycation end‐products (AGEs) are increased in situations with hyperglycemia and oxidative stress such as diabetes mellitus. They are products of nonenzymatic glycation and oxidation of proteins and lipids.
Martin, Busch, Sybille, Franke, Christiane, Rüster, Gunter, Wolf   +3 more
openaire   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Research Progress on Advanced Glycation End Products in Aging-related Diseases

Guoji laonian yixue zazhi
Aging is an inherent physiological phenomenon that occurs throughout human life. Numerous theories have been proposed to elucidate the distinctive features of aging, encompassing oxidative stress, imbalances in protein homeostasis, deterioration of gene ...
Yanling Shen, Yunbo Zhang, Chenghong Liu, Shenhong Gu   +3 more
doaj   +1 more source

Elevated level of the soluble receptor for advanced glycation end-products involved in sarcopenia: an observational study [PDF]

, 2021
Shou‐En Wu, Yi‐Lin Chiu, Tung‐Wei Kao, Wei‐Liang Chen   +3 more
openalex   +1 more source