Results 61 to 70 of about 120,642 (347)
Advanced Glycation End Products and Receptor for Advanced Glycation End Products in AA Amyloidosis
The American Journal of Pathology, 2003 Advanced glycation end products (AGEs) may be involved in either amyloidogenesis or complications related to amyloid. We hypothesized that AGEs may influence the pathogenesis of AA amyloidosis, and investigated the spatial and temporal relationship between AGEs, carboxy methyl lysine (CML), the AGE receptor (RAGE), and AA amyloid in humans and mice ...
Christoph, Röcken +8 more
openaire +3 more sources
Advanced glycation end products and diabetic retinopathy [PDF]
Journal of Ocular Biology, Diseases, and Informatics, 2012 Studies have established hyperglycemia as the most important factor in the progress of vascular complications. Formation of advanced glycation end products (AGEs) correlates with glycemic control. The AGE hypothesis proposes that hyperglycemia contributes to the pathogenesis of diabetic complications including retinopathy.
Yashodhara, Sharma +4 more
openaire +2 more sources
Cogent Food & Agriculture, 2021 Glycation is a non-enzymatic biochemical reaction between reducing sugars and amino acids, causing the crosslinking and rearrangement of glycated proteins, leading to irreversible formation of Advanced Glycation End products (AGEs).
Alpana Pande +4 more
doaj +1 more source
Journal of the Formosan Medical Association, 2021 Background/Purpose: Periodontal disease and diabetes mellitus (DM) are both chronic inflammatory and highly prevalent diseases. A large amount of evidence suggested that the accumulation of oxidative stress plays a significant role in the deterioration ...
Chia-Ming Liu +5 more
doaj +1 more source
From human Megakaryocytes to platelets: Effects of aspirin on high-mobility group Box 1/receptor for advanced glycation end products axis [PDF]
, 2018 Platelets (PLTs) are the major source of high-mobility group box 1 (HMGB1), a protein that is involved in sterile inflammation of blood vessels and thrombosis.
Alessandra Zicari +9 more
core +2 more sources
International Archives of Otorhinolaryngology, 2016 Introduction High mobility group box 1 is a versatile protein involved in gene transcription, extracellular signaling, and response to inflammation. Extracellularly, high mobility group box 1 binds to several receptors, notably the receptor for advanced ...
Austin Nguyen +4 more
doaj +1 more source
Methylglyoxal-dependent glycative stress and deregulation of SIRT1 functional network in the ovary of PCOS mice [PDF]
, 2020 Advanced glycation end-products (AGEs) are involved in the pathogenesis and consequences of polycystic ovary syndrome (PCOS), a complex metabolic disorder associated with female infertility.
Amicarelli, F +10 more
core +1 more source
The Role of Advanced Glycation End Products and Its Soluble Receptor in Kidney Diseases
International Journal of Molecular Sciences, 2022 Patients with chronic kidney disease (CKD) are more prone to oxidative stress and chronic inflammation, which may lead to an increase in the synthesis of advanced glycation end products (AGEs).
Mieke Steenbeke +5 more
semanticscholar +1 more source
Fibroblast viability and phenotypic changes within glycated stiffened three-dimensional collagen matrices [PDF]
, 2015 Background: There is growing interest in the development of cell culture assays that enable the rigidity of the extracellular matrix to be increased. A promising approach is based on three-dimensional collagen type I matrices that are stiffened by cross ...
Alcaraz Casademunt, Jordi +12 more
core +1 more source
Advanced glycation end products in diabetic retinopathy and phytochemical therapy
Frontiers in Nutrition, 2022 Advanced glycation end products (AGEs) are generated by the nonenzymatic glycation of proteins or lipids. Diabetic retinopathy (DR) is one common complication in patients with diabetes.
Qingzheng Kang +3 more
semanticscholar +1 more source