Results 71 to 80 of about 8,200,615 (297)
Advanced Science, EarlyView.Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai +12 more
wiley +1 more source
Research Progress on Advanced Glycation End Products in Aging-related Diseases
Guoji laonian yixue zazhiAging is an inherent physiological phenomenon that occurs throughout human life. Numerous theories have been proposed to elucidate the distinctive features of aging, encompassing oxidative stress, imbalances in protein homeostasis, deterioration of gene ...
Yanling Shen +3 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley +1 more source
, 2010 Background and purpose: Our team previously demonstrated that diabetes induces a deterioration in vascular dynamics, in parallel with the enhanced formation of advanced glycation end products.
張國柱;梁金銅;蔡佩珊;吳明修;許寬立 +1 more
core +1 more source
Advanced glycation end-products in liver diseases: Meta analysis
, 2021 A meta-analysis examining serum levels of advanced glycation end-products in non-alcoholic fatty-liver disease (NAFLD) and alcoholic liver disease (ALD).
Kamil Litwinowicz
core +1 more source
Vascular Effects of Dietary Advanced Glycation End Products
International Journal of Endocrinology, 2015 Evidence has accumulated lately demonstrating that advanced glycation end products (AGEs) play an important role in the development of diabetic and cardiovascular complications as well as the development of other chronic diseases.
Alin Stirban, Diethelm Tschöpe
doaj +1 more source
, 2017 Diabetic myopathy, a less studied complication of diabetes, exhibits the clinical observations characterized by a less muscle mass, muscle weakness and a reduced physical functional capacity.
蔡克嵩;楊庭華;詹鼎正;劉興華;姜至剛;楊榮森 +1 more
core +1 more source
Arthroscopy, EarlyView.Purpose To assess the feasibility of a deep learning model for predicting early structural integrity after arthroscopic rotator cuff repair (ARCR) using intraoperative arthroscopic images obtained after the double‐row bridging repair technique. Methods This retrospective study included patients who underwent ARCR between January 2016 and June 2024 ...
Kuan‐Ting Wu +5 more
wiley +1 more source
Toxicity of advanced glycation end products (Review)
Biomedical Reports, 2021 Advanced glycation end-products (AGEs) are proteins or lipids glycated nonenzymatically by glucose, or other reducing sugars and their derivatives, such as glyceraldehyde, glycolaldehyde, methyloglyoxal and acetaldehyde. There are three different means of AGE formation: i) Maillard reactions, the polyol pathway and lipid peroxidation.
openaire +4 more sources
BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source