Results 131 to 140 of about 3,108,169 (356)

Therapeutic potential of bleomycin plus suicide or interferon-β gene transfer combination for spontaneous feline and canine melanoma [PDF]

, 2017
We originated and characterized melanoma cell lines derived from tumors of two feline and two canine veterinary patients. These lines reestablished the morphology, physiology and cell heterogeneity of their respective parental tumors.
Agnetti, Lucrecia, Finocchiaro, Liliana Maria Elena, Fondello, Chiara, Glikin, Gerardo Claudio, Villaverde, Marcela Solange   +4 more
core   +1 more source

Five-Year Survival and Correlates Among Patients With Advanced Melanoma, Renal Cell Carcinoma, or Non–Small Cell Lung Cancer Treated With Nivolumab

JAMA Oncology, 2019
This secondary analysis of the phase 1 CA209-003 clinical trial assesses the 5-year survival and other related factors among patients with advanced melanoma, renal cell carcinoma, or non–small cell lung cancer receiving nivolumab.
S. Topalian, F. Hodi, J. Brahmer, S. Gettinger, David C. Smith, D. McDermott, J. Powderly, J. Sosman, J. Sosman, M. Atkins, M. Atkins, P. Leming, D. Spigel, S. Antonia, A. Drilon, J. Wolchok, R. Carvajal, R. Carvajal, M. McHenry, F. Hosein, C. Harbison, J. Grosso, M. Sznol   +22 more
semanticscholar   +1 more source

Advanced Melanoma

Hematology/Oncology Clinics of North America, 2021
Alexandra M. Haugh, April K.S. Salama, Douglas B. Johnson   +2 more
openaire   +2 more sources

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

Advanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung, Emie Humann, Joshua M. Price, Yoav Binenbaum, Azra Haseki, Sanjana Iyer, David J. Mooney   +6 more
wiley   +1 more source

Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]

, 2014
Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Aguilar-Guzmán, L, Bennett, DC, Bieneck, S, Burzio, V, Fernandez, JG, Hossain, M, Leyton, L, Lobos-Gonzalez, L, Muñoz, N, Quest, AF, Silva, V, Sviderskaya, EV   +11 more
core   +2 more sources

Five-Year Outcomes With Nivolumab in Patients With Wild-Type BRAF Advanced Melanoma

Journal of Clinical Oncology, 2020
PURPOSE The CheckMate 066 trial investigated nivolumab monotherapy as first-line treatment for patients with previously untreated BRAF wild-type advanced melanoma. Five-year results are presented herein.
C. Robert, G. Long, B. Brady, C. Dutriaux, A. D. Di Giacomo, L. Mortier, P. Rutkowski, J. Hassel, C. McNeil, E. Kalinka, C. Lebbé, J. Charles, M. Hernberg, K. Savage, V. Chiarion-Sileni, C. Mihalcioiu, C. Mauch, A. Arance, F. Cognetti, L. Ny, H. Schmidt, D. Schadendorf, H. Gogas, Jesús Zoco, S. Re, P. Ascierto, V. Atkinson   +26 more
semanticscholar   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Dermatological Malignancies at a University Teaching Hospital in north-western Tanzania: A Retrospective Review of 154 Cases [PDF]

, 2012
Dermatological malignancies are among the most common form of cancers and the global incidence has been increasing at an alarming rate. A retrospective study was conducted to determine the prevalence, histopathological pattern, anatomical distribution ...
Chalya, Phillipo L., Gilyoma, Japhet M., Kahima, Kahima J., Kanumba, Emmanuel S., Masalu, Nestory, Mawala, Brian, Rambau, Peter   +6 more
core   +2 more sources

Recent Advances in Melanoma Biology

The Oncologist, 2004
Abstract Learning Objectives After completing this course, the reader will be able to: Identify the epidemiological evidence supporting the association of intermittent sun exposure with melanoma. Discuss the role of cell adhesion molecules in melanoma progression.
Cliff, Perlis, Meenhard, Herlyn
openaire   +2 more sources

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

Advanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi, Sang Won Lee, Mohammad Abrar Uddin, Sina Hassanpoor, Neha Suvindran, Katherine Le, Harun Arkaz, Harishkumar Narayana, Saeid Soltanian, Danial Khorsandi, Negar Hosseinzadeh Kouchehbaghi, Taeil Kim, Yangzhi Zhu   +12 more
wiley   +1 more source