Results 131 to 140 of about 175,837 (263)

Predicting immune-related thyroiditis using polygenic risk scores in patients with advanced melanoma. [PDF]

J Immunother Cancer
Tarhini AA, Khaksar MA, Chen Z, Lee SJ, Stephen Hodi F, Li T, Yoder SJ, Streicher H, Sondak VK, Kirkwood JM, Wang X, Kanetsky PA.   +11 more
europepmc   +1 more source

Clinical Significance of PD‐L1 and HLA Expression in Esophageal Squamous Cell Carcinoma in Response to Immunotherapy

Annals of Gastroenterological Surgery, EarlyView.
This study evaluated immune‐related biomarkers in esophageal squamous cell carcinoma treated with immune checkpoint inhibitors after postoperative recurrence. PD‐L1 expression in tumor‐associated macrophages and tumor cells, together with HLA class I downregulation and HLA‐DR expression, were associated with favorable responses to immunotherapy.
Kosuke Kanemitsu, Yoshiyuki Tagayasu, Yoshihiro Komohara, Cheng Pan, Rin Yamada, Yukio Fujiwara, Kazuto Harada, Keisuke Kosumi, Yoshifumi Baba, Masaaki Iwatsuki   +9 more
wiley   +1 more source

Immune classification of advanced melanoma identifies non-responders to anti-PD1 therapy. [PDF]

Cancer Immunol Immunother
Gámez-Pozo A, Trilla-Fuertes L, Becerril-Gómez F, Lalanda-Delgado P, Soriano V, Garicano Goldaraz F, Lecumberri MJ, Rodríguez de la Borbolla M, Majem M, Pérez-Ruiz E, González-Cao M, Oramas J, López-Vacas R, Magdaleno A, Fra J, Martín-Carnicero A, Corral M, Puértolas T, Ramos-Ruiz R, Espinosa E, Fresno Vara JÁ.   +20 more
europepmc   +1 more source

Innovations in Gastric Cancer Surgery During Early Minimally Invasive Era and Future Perspectives

Annals of Gastroenterological Surgery, EarlyView.
With continuing revelations in tumor biology and the emergence of artificial intelligence, new horizons for surgical innovation are opening. At the center of this transformative journey stands the innovative surgeon, driven by passion, guided by data, and steadfast in the commitment to patient safety and quality of life.
Reut El‐On, Young‐Woo Kim
wiley   +1 more source

Prognostic Value of Neutrophil Percentage-Albumin Ratio in Patients with Advanced Melanoma Treated with Immune Checkpoint Inhibitors. [PDF]

Curr Oncol
Eken E, Güneyin EA, Büyükkurt E, Yıldız F, Bilici M, Ayman CD.   +5 more
europepmc   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Meta-analytic microbiome target discovery for immune checkpoint inhibitor response in advanced melanoma. [PDF]

Commun Med (Lond)
Zhang X, Mallick H, Rahnavard A.
europepmc   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Does tumor-infiltrating lymphocyte therapy improve survival outcomes in patients with advanced melanoma? [PDF]

Front Med (Lausanne)
Ridley-Parish P.
europepmc   +1 more source

Diabetic Retinopathy Classification With Convolutional Neural Networks Designed by the Fuzzy Grey Wolf Optimizer With Parameter Adaptation

AI &Innovation, EarlyView.
ABSTRACT The detection and classification of diseases have become a field of interest for artificial intelligence in recent years, where the development of methods and models that allow support for specialists in different health fields has allowed early detection of diseases and the provision of timely treatment to patients.
Rodrigo Cordero‐Martínez, Daniela Sánchez, Patricia Melin   +2 more
wiley   +1 more source