Results 1 to 10 of about 596,319 (219)

Clinical adoptive regulatory T Cell therapy: State of the art, challenges, and prospective

Frontiers in Cell and Developmental Biology, 2023
Rejection of solid organ transplant and graft versus host disease (GvHD) continue to be challenging in post transplantation management. The introduction of calcineurin inhibitors dramatically improved recipients’ short-term prognosis.
Leila Amini, Leila Amini, Jaspal Kaeda, Enrico Fritsche, Andy Roemhild, Daniel Kaiser, Petra Reinke, Petra Reinke   +7 more
doaj   +1 more source

Specific Anti-SARS-CoV-2 Humoral and Cellular Immune Responses After Booster Dose of BNT162b2 Pfizer-BioNTech mRNA-Based Vaccine: Integrated Study of Adaptive Immune System Components

Frontiers in Immunology, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is modifying human activity all over the world with significant health and economic burden. The advent of the SARS-CoV-2 pandemic prompted the
Rosalia Busà, Maria Concetta Sorrentino, Giovanna Russelli, Giandomenico Amico, Giandomenico Amico, Vitale Miceli, Monica Miele, Monica Miele, Mariangela Di Bella, Mariangela Di Bella, Francesca Timoneri, Francesca Timoneri, Alessia Gallo, Giovanni Zito, Daniele Di Carlo, Pier Giulio Conaldi, Matteo Bulati   +16 more
doaj   +1 more source

Defining in vitro topical antimicrobial and antibiofilm activity of epoxy-tigliane structures against oral pathogens

Journal of Oral Microbiology, 2023
Background Peri-implantitis has become an inexorable clinical challenge in implantology. Topical immunomodulatory epoxy-tiglianes (EBCs), derived from the Queensland blushwood tree, which induce remodeling and resolve dermal infection via induction of ...
Wenya Xue, Manon F. Pritchard, Saira Khan, Lydia C. Powell, Joana Stokniene, Jingxiang Wu, Nicholas Claydon, Paul Reddell, David W. Thomas, Katja E. Hill   +9 more
doaj   +1 more source

Immune Response after the Fourth Dose of SARS-CoV-2 mRNA Vaccine Compared to Natural Infection in Three Doses’ Vaccinated Solid Organ Transplant Recipients

Viruses, 2022
Solid organ transplant recipients (SOTRs) show higher rates of COVID-19 breakthrough infection than the general population, and nowadays, vaccination is the key preventative strategy.
Rosalia Busà, Giovanna Russelli, Monica Miele, Maria Concetta Sorrentino, Mariangela Di Bella, Francesca Timoneri, Giuseppina Di Mento, Alessandra Mularoni, Patrizio Vitulo, Pier Giulio Conaldi, Matteo Bulati   +10 more
doaj   +1 more source

Mesenchymal stromal cells for the prophylaxis and treatment of graft-versus-host disease—a meta-analysis

Stem Cell Research & Therapy, 2020
Background Graft-versus-host disease (GvHD) is the main life-threatening complication of allogeneic hematopoietic stem cell transplantation (HSCT). Thirty to 80% of GvHD patients do not respond to first-line treatment and a second-line treatment is not ...
Cynthia Morata-Tarifa, María del Mar Macías-Sánchez, Antonio Gutiérrez-Pizarraya, Rosario Sanchez-Pernaute   +3 more
doaj   +1 more source

Alginate oligosaccharides enhance diffusion and activity of colistin in a mucin-rich environment

Scientific Reports, 2022
In a number of chronic respiratory diseases e.g. cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD), the production of viscous mucin reduces pulmonary function and represents an effective barrier to diffusion of inhaled therapies e.g ...
Joana Stokniene, Mathieu Varache, Philip D. Rye, Katja E. Hill, David W. Thomas, Elaine L. Ferguson   +5 more
doaj   +1 more source

Analysis of the Specific Immune Response after the Third Dose of mRNA COVID-19 Vaccines in Organ Transplant Recipients: Possible Spike-S1 Reactive IgA Signature in Protection from SARS-CoV-2 Infection

Microorganisms, 2022
Background: Several studies have indicated that anti-SARS-CoV-2 mRNA vaccinations are less effective in inducing robust immune responses among solid organ transplant recipients (SOTRs) compared with the immunocompetent. The third dose of vaccine in SOTRs
Monica Miele, Rosalia Busà, Giovanna Russelli, Maria Concetta Sorrentino, Mariangela Di Bella, Francesca Timoneri, Giampiero Vitale, Elisa Calzolari, Patrizio Vitulo, Alessandra Mularoni, Pier Giulio Conaldi, Matteo Bulati   +11 more
doaj   +1 more source

Imaging of hepatocellular carcinoma recurrence after liver transplantation

Insights into Imaging, 2023
Liver transplantation (LT) provides the highest survival benefit to patients with unresectable hepatocellular carcinoma (HCC). The Milan criteria have been developed for the selection of LT candidates with the goal of improving survival and maintaining ...
Giuseppe Mamone, Settimo Caruso, Mariapina Milazzo, Giorgia Porrello, Ambra Di Piazza, Giovanni Gentile, Vincenzo Carollo, Francesca Crinò, Gianluca Marrone, Gianvincenzo Sparacia, Luigi Maruzzelli, Roberto Miraglia, Salvatore Gruttadauria   +12 more
doaj   +1 more source

Generation of induced pluripotent stem cell lines from helper and cytotoxic T cells of healthy individuals

Stem Cell Research, 2023
T lymphocytes are the most abundant mononuclear blood cells and can serve as a source for generating induced pluripotent stem cells (iPSCs) for disease modeling or drug development.
Timothy Kamaldinov, Linyi Zhang, Lin Wang, Zhaohui Ye   +3 more
doaj   +1 more source

Advanced therapies [PDF]

Farmacia Hospitalaria, 2020
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María Jesús Lamas-Díaz, César Gernández-García   +1 more
doaj   +1 more source