Results 11 to 20 of about 585,342 (345)
Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs [PDF]
Background: Children are frequently prescribed medication off-label, meaning there has not been sufficient testing of the medication to determine its safety or effectiveness. The main reason this safety knowledge is lacking is due to ethical restrictions that prevent children from being included in the majority of clinical trials.
Aickelin, U.+11 more
arxiv +9 more sources
Refining adverse drug reaction signals by incorporating interaction variables identified using emergent pattern mining [PDF]
Purpose: To develop a framework for identifying and incorporating candidate confounding interaction terms into a regularised cox regression analysis to refine adverse drug reaction signals obtained via longitudinal observational data. Methods: We considered six drug families that are commonly associated with myocardial infarction in observational ...
Bien+33 more
arxiv +6 more sources
Adverse cutaneous drug reaction
In everyday clinical practice, almost all physicians come across many instances of suspected adverse cutaneous drug reactions (ACDR) in different forms.
Nayak Surajit, Acharjya Basanti
doaj +4 more sources
The incidence of adverse reactions to drugs [PDF]
O. L. Wade
openalex +5 more sources
SummaryAdverse drug reactions are a cause of significant morbidity and mortality to patients and a source of financial burden to the healthcare system. Of the wide spectrum of adverse drug reactions, the most concerning to the anaesthetist remain anaphylaxis and malignant hyperthermia.
Ferner, RE, McGettigan, P
+9 more sources
Adverse Cutaneous Drug Reaction [PDF]
Drug-induced skin disease or cutaneous adverse drug reaction (CADR) is a term encompassing clinical manifestations of the skin, induced by drugs or their metabolites.
Elzwi, Samia
core +2 more sources
Adverse drug reactions (ADRs) remain a challenge in modern healthcare, particularly given the increasing complexity of therapeutics, an ageing population and rising multimorbidity. This article summarises some of the key facts about ADRs and explores aspects relating to their prevention, diagnosis, reporting and management in current clinical practice.
Jamie J, Coleman, Sarah K, Pontefract
openaire +4 more sources
Adverse Effects of Cholinesterase Inhibitors in Dementia, According to the Pharmacovigilance Databases of the United-States and Canada. [PDF]
This survey analyzes two national pharmacovigilance databases in order to determine the major adverse reactions observed with the use of cholinesterase inhibitors in dementia.
Abagyan, Ruben+4 more
core +14 more sources