Results 21 to 30 of about 1,084,213 (290)

Drug-Induced Severe Cutaneous Adverse Reactions: Insights Into Clinical Presentation, Immunopathogenesis, Diagnostic Methods, Treatment, and Pharmacogenomics

Frontiers in Pharmacology, 2022
SCARs are rare and life-threatening hypersensitivity reactions. In general, the increased duration of hospital stays and the associated cost burden are common issues, and in the worst-case scenario, they can result in mortality.
Therdpong Tempark, Therdpong Tempark, Shobana John, Shobana John, Pawinee Rerknimitr, Pawinee Rerknimitr, Patompong Satapornpong, Patompong Satapornpong, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem   +13 more
doaj   +1 more source

A clinical study of morphological patterns of cutaneous adverse drug reaction and its causality assessment in tertiary care hospital of central India [PDF]

, 2020
Background: Adverse reactions to drugs are as old as drug. Cutaneous adverse drug reactions are the most common type of drug reaction. Most cutaneous adverse drug reactions are important as they are frequently the reason for discontinuation of drug ...
Shende, Tanaji R., Siddiqui, Riyaz A.
core   +2 more sources

Adverse reactions of amiodarone [PDF]

, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo, Ciacciarelli, Marco, Colunga Biancatelli, Ruben Ml, Congedo, Viviana, Iuliano, Luigi, Polidoro, Alessandro   +5 more
core   +1 more source

Fixed drug eruption associated with fixed combination of fluoroquinolone-nitroimidazole [PDF]

, 2021
Fixed drug eruptions (FDE) are cutaneous adverse drug reaction characterized by well demarcated erythematous plaques which on removal of the offending agent resolves with residual hyperpigmentation patches at the site.
Kiruthika, S., Meenakshi, R., Nitya, S., Shanthi, M.   +3 more
core   +2 more sources

Healthcare professionals’ pharmacovigilance knowledge and adverse drug reaction reporting behavior and factors determining the reporting rates

Journal of Drug Assessment, 2019
Background: Spontaneous adverse drug reaction (ADR) reports prepared by healthcare professionals (HCPs) are the backbone of collecting post-marketing safety data.
M. Güner, P. Ekmekci
semanticscholar   +1 more source

PEG-Derivatized Dual-Functional Nanomicelles for Improved Cancer Therapy

Frontiers in Pharmacology, 2019
Polymeric micelles have attracted considerable attention for effective delivery of poorly water-soluble cancer drugs. Polyethylene glycol (PEG), which has been approved for human use by the US Food and Drug Administration, is the most commonly used ...
Yanping Li, Ting Zhang, Qinhui Liu, Jinhan He, Jinhan He   +4 more
doaj   +1 more source

Study of adverse drug reactions of atypical antipsychotic drugs in the department of psychiatry in a tertiary care hospital of Assam

Open Journal of Psychiatry and Allied Sciences, 2017
Objective: To monitor the adverse drug reactions (ADRs) of atypical antipsychotic drugs in the outpatient department (OPD) of psychiatry in Silchar Medical College and Hospital (SMCH) of Assam, and also to find out the causality and severity of ADRs ...
Pinaki Chakravarty, Parthajyoti Neog, Babul Dewan   +2 more
doaj   +1 more source

Adverse Reactions to Drugs [PDF]

Postgraduate Medicine, 1965
The present trend toward polypharmacy increases the likelihood of adverse drug reactions and obscures the relationship of drugs to complications. Both host factors and drug factors predispose to the development of an adverse reaction. Reactions may be related to therapeutic or nontherapeutic effects of drugs. Other categories include allergic reactions
openaire   +6 more sources

Pharmacovigilance from social media: mining adverse drug reaction mentions using sequence labeling with word embedding cluster features

J. Am. Medical Informatics Assoc., 2015
Objective Social media is becoming increasingly popular as a platform for sharing personal health-related information. This information can be utilized for public health monitoring tasks, particularly for pharmacovigilance, via the use of natural ...
Azadeh Nikfarjam, A. Sarker, K. O’Connor, Rachel E. Ginn, G. Gonzalez-Hernandez   +4 more
semanticscholar   +1 more source

The Role of Sirt6 in Obesity and Diabetes

Frontiers in Physiology, 2018
Sirt6 is one of the sirtuin family members, a kind of NAD+-dependent histone deacetylase and ADP-ribose transferase enzyme. It has an important role in physiological and pathological processes, regulating aging, cancer, obesity, insulin resistance ...
Jiangying Kuang, Jiangying Kuang, Lei Chen, Lei Chen, Qin Tang, Qin Tang, Jinhang Zhang, Jinhang Zhang, Yanping Li, Yanping Li, Jinhan He, Jinhan He   +11 more
doaj   +1 more source