Results 41 to 50 of about 1,084,213 (290)

Idiopathic non-histaminergic acquired angioedema: a case series and discussion of published clinical trials

Clinical and Translational Allergy, 2017
Background Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease for which there are no available laboratory parameters to clearly define the disorder. Therapy is often difficult and various treatment options have been proposed. In
Martin Christian Bucher, Tatjana Petkovic, Arthur Helbling, Urs Christian Steiner   +3 more
doaj   +1 more source

Factors Affecting Adverse Drug Reaction Reporting of Healthcare Professionals and Their Knowledge, Attitude, and Practice towards ADR Reporting in Nekemte Town, West Ethiopia

BioMed Research International, 2016
Background. Adverse drug reactions are global problems of major concern. Adverse drug reaction reporting helps the drug monitoring system to detect the unwanted effects of those drugs which are already in the market. Aims.
Lense Temesgen Gurmesa, Mohammed Gebre Dedefo   +1 more
semanticscholar   +1 more source

Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients

Journal of Immunology Research, 2018
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients.
Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn   +17 more
doaj   +1 more source

Irisin Is Controlled by Farnesoid X Receptor and Regulates Cholesterol Homeostasis

Frontiers in Pharmacology, 2019
ObjectiveThe aim of this study was to investigate whether the nuclear receptor farnesoid X receptor (FXR) could regulate FNDC5/Irisin expression and the role of Irisin in hyperlipidemia and atherosclerosis in ApoE-/- mice.Methods and ResultsWe treated ...
Hong Li, Hong Li, Jing Shen, Jing Shen, Tong Wu, Tong Wu, Jiangying Kuang, Jiangying Kuang, Qinhui Liu, Shihai Cheng, Shihai Cheng, Shiyun Pu, Shiyun Pu, Lei Chen, Lei Chen, Rui Li, Rui Li, Yanping Li, Yanping Li, Min Zou, Zhiyong Zhang, Wei Jiang, Aijuan Qu, Jinhan He, Jinhan He   +24 more
doaj   +1 more source

Efficacy of a Modified Sepsis System on the Mortality Rate of Septic Shock Patients in the Emergency Department of Siriraj Hospital

Journal of Health Science and Medical Research (JHSMR), 2022
Objective: To compare the 28-day mortality rate between pre- and post-implementation of a modified sepsis fast-track system. Material and Methods: A cross-sectional cohort study was conducted at the Emergency Room (ER) of Siriraj Hospital, Bangkok.
Natvadee Rakpraisuthepsiri, Usapan Surabenjawong, Chok Limsuwat, Ploylarp Lertvipapath   +3 more
doaj   +1 more source

Adverse drug reaction and causality assessment scales

Lung India, 2011
Syed Ahmed Zaki
doaj   +2 more sources

Magnitude of adverse drug reaction and associated factors among HIV-infected adults on antiretroviral therapy in Hiwot Fana specialized university hospital, eastern Ethiopia [PDF]

, 2016
Introduction: human immunodefiecency virus infected patients did not adhere correctly to their Antiretroviral Therapy because of the drugs adverse effects. Thus, continuous evaluation of the adverse effect of Antiretroviral Therapy will help to make more
Mitiku, Habtamu, Teklemariam, Zelalem, Weldegebreal, Fitsum   +2 more
core   +3 more sources

MRGPRX2 and Adverse Drug Reactions [PDF]

Frontiers in Immunology, 2021
Many adverse reactions to therapeutic drugs appear to be allergic in nature, and are thought to be triggered by patient-specific Immunoglobulin E (IgE) antibodies that recognize the drug molecules and form complexes with them that activate mast cells. However, in recent years another mechanism has been proposed, in which some drugs closely associated ...
openaire   +4 more sources

Sex differences in pharmacokinetics predict adverse drug reactions in women

Biology of Sex Differences, 2020
Women experience adverse drug reactions, ADRs, nearly twice as often as men, yet the role of sex as a biological factor in the generation of ADRs is poorly understood.
I. Zucker, B. Prendergast
semanticscholar   +1 more source

Enhancing Communication about Paediatric Medicines: Lessons from a Qualitative Study of Parents' Experiences of Their Child's Suspected Adverse Drug Reaction [PDF]

, 2012
Background: There is little research on parents’ experiences of suspected adverse drug reactions in their children and hence little evidence to guide clinicians when communicating with families about problems associated with medicines.
Arnott, J., Hesselgreaves, H., Nunn, A.J., Peak, M., Pirmohamed, M., Smyth, R.L., Turner, M.A., Young, B.   +7 more
core   +6 more sources