Results 251 to 260 of about 103,305 (302)

T‐cell exhaustion from a multiomics perspective: Differentiation mechanisms and regulatory networks in the journey from progenitor‐Exhausted T cells to terminally exhausted T cells

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
(1) Core Process: Persistent antigen, from TDLNs to TME, drives Tpex → Tex‐int → Tex‐term differentiation. (2) Multiomics Regulation: This fate transition is orchestrated by a co‐ordinated, multi‐layered molecular network. (3) Functional Outcome: Dysregulated signalling and surging co‐inhibitory receptors lock in proliferative arrest and functional ...
Tong Zhu   +5 more
wiley   +1 more source

Ameliorative Effects of Aerobic Exercise Combined With Lycium barbarum Polysaccharide‐Mediated Gut Microbiota Remodeling on Glycolipid Abnormalities in Type 2 Diabetic Rats

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
This schematic illustrates the protective effects of aerobic exercise and Lycium barbarum polysaccharide in a rat model of type 2 diabetes mellitus (T2DM), which was induced by high‐fat/high‐sugar feeding and streptozotocin (STZ) injection. Both interventions target the gut microbiota to promote short‐chain fatty acid production, thereby regulating ...
Jing‐feng Wang   +3 more
wiley   +1 more source

Anticancer Molecular Mechanisms of Phytosterols: An Updated Review on Clinical Trials

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Phytosterols, a form of naturally occurring substance structurally related to cholesterol, have been getting considerable interest due to their possible anticancer properties. Phytosterols induce apoptosis, block the cell cycle, and abrogate the invasion and metastasis of cancer cells, offering a multi‐manifestation treatment of cancer.
Muhammad Shahbaz   +14 more
wiley   +1 more source

Correction: Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis. [PDF]

open access: yesJ Nanobiotechnology
Wang M   +15 more
europepmc   +1 more source

SENP1 inhibits aerobic glycolysis in Aβ<sub>1-42</sub>-incubated astrocytes by promoting PUM2 deSUMOylation. [PDF]

open access: yesCell Biol Toxicol
Liu Q   +8 more
europepmc   +1 more source

FOXK1 and FOXK2 regulate aerobic glycolysis

open access: yesNature, 2019
Adaptation to the environment and extraction of energy are essential for survival. Some species have found niches and specialized in using a particular source of energy, whereas others-including humans and several other mammals-have developed a high degree of flexibility1.
Stefano Bartesaghi   +2 more
exaly   +3 more sources

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