CCDC86-BHLHE40-ATF3 axis promotes aerobic glycolysis and tumor development in glioma. [PDF]
Liu J +6 more
europepmc +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
<i>Toxoplasma gondii</i> GRA16 Suppresses Aerobic Glycolysis by Downregulating c-Myc and TERT Expressions in Colorectal Cancer Cells. [PDF]
Lee JE, Seo SH, Ham DW, Shin EH.
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Hepatocellular carcinoma cells downregulate PGAM2 via SIRT2-mediated deacetylation modification to enhance aerobic glycolysis. [PDF]
Wang Z +10 more
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Innovative PDK1-Degrading PROTACs Transform Cancer Aerobic Glycolysis and Induce Immunogenic Cell Death in Breast Cancer. [PDF]
Deng A +9 more
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Correction to "SPARC Promotes Aerobic Glycolysis and 5-Fluorouracil Resistance in Colorectal Cancer Through the STAT3/HK2 Axis". [PDF]
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DLAT activates EMT to promote HCC metastasis by regulating GLUT1-mediated aerobic glycolysis. [PDF]
Yin Q +9 more
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Enhanced Antitumor Activity of Korean Black Soybean Cultivar 'Soman' by Targeting STAT-Mediated Aerobic Glycolysis. [PDF]
Park SH +10 more
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Correction: LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer. [PDF]
Wang Y +18 more
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Aerobic glycolysis during lymphocyte proliferation
Nature, 1976GLYCOLYSIS, for most mammalian cells, is only a prelude to the complete respiratory oxidation of glucose. Lactate production is usually barely, if at all, detectable in aerobic conditions1. Consequently, when Warburg2,3 observed that various tumours showed active aerobic glycolysis, he postulated that defective tumour cell respiration was the reason ...
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