Results 71 to 80 of about 12,726 (261)

Optimization Design of Blades Based on Multi-Objective Particle Swarm Optimization Algorithm

open access: yesJournal of Marine Science and Engineering
Among renewable energy sources derived from the ocean, wind power has developed rapidly. This article proposes an optimization algorithm framework that integrates two objectives: aerodynamic shape optimization and structural optimization.
Zihao Li   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Improving aerodynamic performance of intermodal trains through optimisation of loading plans

open access: yesArchives of Transport
This paper addresses the improvement of energy efficiency in intermodal freight trains by reducing aerodynamic drag through optimisation of container arrangement on railcars.
Karol Nehring, Łukasz Kiszkowiak
doaj   +1 more source

Design of a wind turbine rotor for maximum aerodynamic efficiency

open access: yesWind Energy, 2008
AbstractThe design of a three‐bladed wind turbine rotor is described, where the main focus has been highest possible mechanical power coefficient, CP, at a single operational condition. Structural, as well as off‐design, issues are not considered, leading to a purely theoretical design for investigating maximum aerodynamic efficiency.The rotor is ...
Johansen, Jeppe   +4 more
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Numerical and experimental study on aerodynamic design for the rear wing of an electric sports car

open access: yesKongqi donglixue xuebao
The rear wing is a core component determining the aerodynamic downforce of sports cars. In the design of electric sports cars, its aerodynamic development faces a fundamental contradiction: enhancing downforce to improve handling stability while ...
Kai Liu   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

EFFECT OF SUV BODY GEOMETRY ON AERODYNAMIC DRAG AND FUEL EFFICIENCY USING CFD

open access: yesScientific Journal of Mechanical Engineering Kinematika
The increasing demand for fuel efficiency in the automotive industry, particularly in the sport utility vehicle (SUV) segment, has intensified research on factors influencing vehicle energy efficiency.
Arifin Oktobrian Winanta   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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