Results 91 to 100 of about 147,005 (295)

Efficient aerodynamic shape optimization by using unsupervised manifold learning to filter geometric features

Engineering Applications of Computational Fluid Mechanics
Many aerodynamic shape optimization methods often focus on utilizing the end-to-end relationship between design variables and aerodynamic performance to find the optimal design, while overlooking the exploration of geometric knowledge of the shape itself.
Long Ma, Xiao-Jing Wu, Wei-Wei Zhang
doaj   +1 more source

Simulating wind turbine interactions using the vorticity transport equations [PDF]

, 2009
The aerodynamic interactions that can occur within a wind farm result in the constituent turbines generating a lower power output than would be possible if each of the turbines were operated in isolation.
Brown, R.E., Fletcher, Timothy M.
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Rapid Method of Integrated Aeropropulsive Analysis for the Conceptual Design of Airbreathing Hypersonic Aircraft

Aerospace
A special feature of airbreathing hypersonic aircraft is the complex coupling between aerodynamic and propulsive performances. This study presents a rapid analysis methodology for the integration of these two critical aspects in the conceptual design of ...
Yalin Dai, Zhouwei Fan, Jian Xu, You He, Xiongqing Yu   +4 more
doaj   +1 more source

Validation of a pair of computer codes for estimation and optimization of subsonic aerodynamic performance of simple hinged-flap systems for thin swept wings [PDF]

Extensive correlations of computer code results with experimental data are employed to illustrate the use of linearized theory attached flow methods for the estimation and optimization of the aerodynamic performance of simple hinged flap systems.
Carlson, Harry W., Darden, Christine M.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aerodynamic Design and Performance Analysis of a Large-Scale Composite Blade for Wind Turbines

Applied Sciences
In this study, we determined an aerodynamic configuration to design structures applying composites for large-scale horizontal-axis wind turbine blades. A new aerodynamic and structural design method for large wind turbine blades is presented.
Semyoung Lim, Sungjin Ahn, Hyunbum Park
doaj   +1 more source

Performance and loads data from a hover test of a 0.658-scale V-22 rotor and wing [PDF]

A hover test of a 0.658-scale model of a V-22 rotor and wing was conducted at the Outdoor Aerodynamic Research Facility at Ames Research Center. The primary objectives of the test were to obtain accurate measurements of the hover performance of the rotor
Betzina, Mark D., Felker, Fort F., Signor, David B., Young, Larry A.   +3 more
core   +1 more source

AiResearch QCGAT engine performance and emissions tests [PDF]

, 1980
Results of aerodynamic performance and emission tests, conducted on a specially designed QCGAT engine in the 17,793-N (4,000 lb) thrust class, are presented. Performance of the AiResearch QCGAT engine was excellent throughout all testing.
Norgren, W. M.
core   +1 more source

Quantification of airfoil geometry-induced aerodynamic uncertainties - comparison of approaches

, 2016
Uncertainty quantification in aerodynamic simulations calls for efficient numerical methods since it is computationally expensive, especially for the uncertainties caused by random geometry variations which involve a large number of variables. This paper
Litvinenko, Alexander, Liu, Dishi, Schillings, Claudia, Schulz, Volker   +3 more
core   +1 more source