Results 21 to 30 of about 20,026 (197)

Apple Peel Flavonoid Fraction 4 Suppresses Breast Cancer Cell Growth by Cytostatic and Cytotoxic Mechanisms

Molecules, 2019
Many dietary flavonoids possess anti-cancer activities. Here, the effect of apple peel flavonoid fraction 4 (AF4) on the growth of triple-negative (MDA-MB-231, MDA-MB-468), estrogen receptor-positive (MCF-7), and HER2-positive (SKBR3) breast cancer cells
Chao-Yu Loung, Wasundara Fernando, H.P. Vasantha Rupasinghe, David W. Hoskin   +3 more
doaj   +1 more source

Asymmetrical Flow Field-Flow Fractionation Methods for Quantitative Determination and Size Characterization of Thiols and for Mercury Size Speciation Analysis in Organic Matter-Rich Natural Waters

Frontiers in Chemistry, 2022
Asymmetrical flow field-flow fractionation (AF4) efficiently separates various macromolecules and nano-components of natural waters according to their hydrodynamic sizes.
Isabelle A. M. Worms, Killian Kavanagh, Elodie Moulin, Nicole Regier, Vera I. Slaveykova   +4 more
doaj   +1 more source

A first principles study of wurtzite-structure MnO [PDF]

, 2003
We present results of a density functional theory study of MnO in the wurtzite structure. Our motivation is provided by recent experiments reporting ferromagnetism in Mn-doped wurtzite structure ZnO.
Gopal, Priya, Spaldin, Nicola, Waghmare, Umesh. V.   +2 more
core   +2 more sources

MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia

Nature Communications, 2023
Aberrant enhancer activation is a key mechanism driving oncogene expression in many cancers. While much is known about the regulation of larger chromosome domains in eukaryotes, the details of enhancer-promoter interactions remain poorly understood ...
Nicholas T. Crump, Alastair L. Smith, Laura Godfrey, Ana M. Dopico-Fernandez, Nicholas Denny, Joe R. Harman, Joseph C. Hamley, Nicole E. Jackson, Catherine Chahrour, Simone Riva, Siobhan Rice, Jaehoon Kim, Venkatesha Basrur, Damian Fermin, Kojo Elenitoba-Johnson, Robert G. Roeder, C. David Allis, Irene Roberts, Anindita Roy, Huimin Geng, James O. J. Davies, Thomas A. Milne   +21 more
doaj   +1 more source

One-Loop Amplitudes in Supersymmetric QCD from MHV Vertices [PDF]

, 2006
The Cachazo-Svrcek-Witten (CSW) rule for efficiently calculating gauge theory amplitudes is extended to N=1 supersymmetric QCD (SQCD), incorporating massless quarks, in a way preserving the manifest supersymmetry.
Badger, Bedford, Bedford, Bern, Bern, Bern, Bern, Bern, Bern, Brandhuber, Brandhuber, Cachazo, Georgiou, Georgiou, Giombi, Hiroshi Kunitomo, Lewin, Mangano, Park, Passarino, Quigley, Su, Witten, Wu, Wu   +24 more
core   +3 more sources

Functional Studies of MLL-AF4 and a Murinized pSer-variant thereof: MLL-AF4 Impairs the Ribosome Biosynthesis Pathway [PDF]

, 2021
Abstract Background: Recent pathomolecular studies on the MLL-AF4 fusion protein revealed that the murinized version of MLL-AF4, the MLL-Af4 fusion protein, was able to induce leukemia when expressed in murine or human hematopoietic stem/progenitor cells (1).
Anna Lena Siemund, Eric Kowarz, Rolf Marschalek   +2 more
openaire   +1 more source

Epigenetic regulator genes direct lineage switching in  MLL/AF4 leukemia [PDF]

Blood, 2022
Abstract The fusion gene MLL/AF4 defines a high-risk subtype of pro-B acute lymphoblastic leukemia. Relapse can be associated with a lineage switch from acute lymphoblastic to acute myeloid leukemia, resulting in poor clinical outcomes caused by resistance to chemotherapies and immunotherapies.
Ricky Tirtakusuma, Katarzyna Szoltysek, Paul Milne, Vasily V. Grinev, Anetta Ptasinska, Paulynn S. Chin, Claus Meyer, Sirintra Nakjang, Jayne Y. Hehir-Kwa, Daniel Williamson, Pierre Cauchy, Peter Keane, Salam A. Assi, Minoo Ashtiani, Sophie G. Kellaway, Maria R. Imperato, Fotini Vogiatzi, Elizabeth K. Schweighart, Shan Lin, Mark Wunderlich, Janine Stutterheim, Alexander Komkov, Elena Zerkalenkova, Paul Evans, Hesta McNeill, Alex Elder, Natalia Martinez-Soria, Sarah E. Fordham, Yuzhe Shi, Lisa J. Russell, Deepali Pal, Alex Smith, Zoya Kingsbury, Jennifer Becq, Cornelia Eckert, Oskar A. Haas, Peter Carey, Simon Bailey, Roderick Skinner, Natalia Miakova, Matthew Collin, Venetia Bigley, Muzlifah Haniffa, Rolf Marschalek, Christine J. Harrison, Catherine A. Cargo, Denis Schewe, Yulia Olshanskaya, Michael J. Thirman, Peter N. Cockerill, James C. Mulloy, Helen J. Blair, Josef Vormoor, James M. Allan, Constanze Bonifer, Olaf Heidenreich, Simon Bomken   +56 more
openaire   +4 more sources

Comparative analysis of the biological characteristics and mechanisms of azole resistance of clinical Aspergillus fumigatus strains

Frontiers in Microbiology, 2023
Aspergillus fumigatus is a common causative pathogen of aspergillosis. At present, triazole resistance of A. fumigatus poses an important challenge to human health globally. In this study, the biological characteristics and mechanisms of azole resistance
Meng Zeng, Meng Zeng, Xue Zhou, Chunhong Yang, Yanfei Liu, Jinping Zhang, Caiyan Xin, Gang Qin, Fangyan Liu, Zhangyong Song   +9 more
doaj   +1 more source

Inter-hemispheric EEG coherence analysis in Parkinson's disease : Assessing brain activity during emotion processing [PDF]

, 2014
Parkinson’s disease (PD) is not only characterized by its prominent motor symptoms but also associated with disturbances in cognitive and emotional functioning.
A Ariatti, A Cronin-Golomb, A Morita, A Suzuki, A Tessitore, AD Lawrence, AD Lawrence, AEB Cancelliere, AF Leuchter, AT Beck, B Pillon, BE Levin, C Dara, C Schröder, CC French, CF Lima, CL Yeager, D Bowers, D Schellberg, E Mohr, G Nolte, GG Celesia, H Cohen, H Hinrichs, H Kober, HL Chen, HM Gray, IH Gotlib, J Busk, J Mikels, J Péron, J Redondo, JA Obeso, JC Shaw, JF Caekebeke, JJ Gross, JM Savitt, JT Yip, K Dujardin, K Sergerie, Kenneth Sundaraj, KH Kim, Khairiyah Mohamad, KM Miller, LC Fonseca, M Lotze, M Murugappan, M. Murugappan, M. Satiyan, MA Guevara, MD Pell, MD Pell, MF Folstein, MI Ventura, MJ Wieser, MJ Wieser, MK Beyer, MM Hoehn, Mohd Iqbal Omar, MY Neufeld, Norlinah Mohamed Ibrahim, P Garrido-Vásquez, P Madeley, P Salgado-Pineda, PC Petrantonakis, PJ Lang, R Adolphs, R Adolphs, R Bastiaanse, R Soikkeli, R Sprengelmeyer, R Yuvaraj, R. Palaniappan, R. Yuvaraj, RA Roemer, RC Oldfield, RJ Davidson, RJR Blair, RW Thatcher, S Jerritta, S Paulmann, SK Hadjidimitriou, T Baumgartner, T Gasser, TF Newton, TP Bouchard, US Clark, Y Kan, Y Wang   +88 more
core   +1 more source

AF4 (ALL1 fused gene from chromosome 4) - AFF1 (AF4/FMR2 family, member 1) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on AFF1 (AF4/FMR2 family, member 1), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +1 more source