Results 81 to 90 of about 159,503 (290)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Mistaken Pedal Pressing during Emergency Braking by Analyzing Pedal Behaviors

SICE Journal of Control, Measurement, and System Integration, 2019
Affective computing has been used to improve computer usability and user interface by considering user's emotion. There is still ample scope for exploration of affective computing especially for applications in a driver assistance system to ...
Rahadian Yusuf, Ivan Tanev, Katsunori Shimohara   +2 more
doaj   +1 more source

A real-time facial expression recognition system for affective computing [PDF]

, 2013
A thesis submitted to the University of London in partial fulfillment to the degree of Doctor of ...
Anderson, Keith William John
core  

Hand2Face: Automatic Synthesis and Recognition of Hand Over Face Occlusions

, 2017
A person's face discloses important information about their affective state. Although there has been extensive research on recognition of facial expressions, the performance of existing approaches is challenged by facial occlusions. Facial occlusions are
Baltrusaitis, Tadas, Hughes, Charles. E., Morency, Louis-philippe, Nojavanasghari, Behnaz   +3 more
core   +1 more source

The development of a rich multimedia training environment for crisis management: using emotional affect to enhance learning [PDF]

, 2011
PANDORA is an EU FP7-funded project developing a novel training and learning environment for Gold Commanders, individuals who carry executive responsibility for the services and facilities identified as strategically critical e.g. Police, Fire, in crisis
Carberry S., D'Mello S., Forbes-Riley K., Yannakakis G.N.   +3 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Predicting cardiovascular disease in patients with mental illness using machine learning

European Psychiatry
Background Cardiovascular disease (CVD) is twice as prevalent among individuals with mental illness compared to the general population. Prevention strategies exist but require accurate risk prediction.
Martin Bernstorff, Lasse Hansen, Kevin Kris Warnakula Olesen, Andreas Aalkjær Danielsen, Søren Dinesen Østergaard   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

EmoTxt: A Toolkit for Emotion Recognition from Text

, 2017
We present EmoTxt, a toolkit for emotion recognition from text, trained and tested on a gold standard of about 9K question, answers, and comments from online interactions. We provide empirical evidence of the performance of EmoTxt.
Calefato, Fabio, Lanubile, Filippo, Novielli, Nicole   +2 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source