Results 171 to 180 of about 533,233 (349)

A Web-Based Transdiagnostic Intervention for Affective and Mood Disorders: Randomized Controlled Trial (Preprint)

, 2017
Bogdan Tudor Tulbure, Andrei Rusu, Florin Alin Sava, Nastasia S l gean, Todd J. Farchione   +4 more
openalex   +1 more source

The Effect of Tryptophan Depletion on Mood in Medication-Free, Former Patients with Major Affective Disorder [PDF]

, 1997
Marco Leyton
openalex   +1 more source

Distribution of Charged Residues Affects the Average Size and Shape of Intrinsically Disordered Proteins [PDF]

, 2022
Greta Bianchi, Marco Mangiagalli, Alberto Barbiroli, Sonia Longhi, Rita Grandori, Carlo Santambrogio, Stefania Brocca   +6 more
openalex   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Physical exercise and catecholamine reuptake inhibitors affect orienting behavior and social interaction in a rat model of attention-deficit/hyperactivity disorder.

, 2021
Andrea M. Robinson, Rachel L. Eggleston, David J. Bucci   +2 more
openalex   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

ATP and major affective disorders: the involvement of P2X receptors in pathophysiology. [PDF]

Purinergic Signal
Mattova S, Simko P, Colzi E, Stammova E, Urbanska N, Grigoroiu-Serbanescu M, Coppi E, Kiskova-Simkova T.   +7 more
europepmc   +1 more source

Benzodiazepine receptor antagonist (flumazenil) does not affect sleep-related breathing disorders [PDF]

, 1996
B. Schönhofer, D. Köhler
openalex   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source