Results 131 to 140 of about 132,244 (301)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Domain-specific and domain-general predictors of math anxiety in adolescents and adults [PDF]
It is well-established that a negative relation exists between math anxiety (MA) and math performance. However, because there has been no systematic quantitative research on the predictors of MA, we conducted three studies in adolescents and adults to ...
Szczygieł, M., Hunt, T., Sarı, M. H.
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Using Differentiated Instruction to Support Teaching and Learning in the Affective Domain
, 2020 While many educational conversations have been shaped by high-stakes testing and accountability that are often associated with the cognitive learning domain (Bloom et al., 1956), recent conversations in education have increasingly centered on the ...
Powell, Cathy G.
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Educational Objectives Taxonomy: Affective Domain [PDF]
مجله ایرانی آموزش در علوم پزشکی, 2004 Alireza Yousefy
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The Affective Domain and Attainment
, 2012 DiSA (Disparities in Student Attainment) Briefing Paper in book 'Achieving Equity and Academic Excellence in Higher Education: Perspectives in an Era of Widening Participation', Palgrave Macmillan; Australia. Eds. Shah, M and McKay, J (2018).
Cureton, Debra, Cousin, Glynis
openaire +1 more source
Affective Domain Applications in Standards-Based Education
, 2014 This research examined the attitudes of teachers toward the affective domain in high versus low levels of standards-based instruction. Teachers from a school district in the suburbs of the greater Seattle, Washington, metropolitan area completed a self ...
Rumbaugh, Wayne
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Nurse Educators\u27 Use of the Affective Domain of Learning in Critical Instruction
, 2016 The purpose of this project was to explore the lived experience of nurse educators’ use of the affective domain in clinical post-conference at the baccalaureate level. Five nursing faculty members who provide clinical instruction to undergraduate nursing
Wagoner, Sarah
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