Results 201 to 210 of about 329,197 (260)

B-cell peripheral tolerance: think dynamics beyond affinity. [PDF]

open access: yesFront Immunol
Yuan PH   +3 more
europepmc   +1 more source
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Principles of Affinity Selection

Cold Spring Harbor Protocols, 2023
The most common application of phage-display technology is the discovery of peptides or proteins that specifically bind some molecule or other substance of interest—for example, antibodies that specifically bind an antigen. The discovery process starts with a library encompassing a very large array of proteins or peptides with a great diversity of ...
openaire   +2 more sources

Selection of imprinted nanoparticles by affinity chromatography [PDF]

open access: yesBiosensors and Bioelectronics, 2009
Soluble molecularly imprinted nanoparticles were synthesised via iniferter initiated polymerisation and separated by size via gel permeation chromatography. Subsequent fractionation of these particles by affinity chromatography allowed the separation of high affinity fractions from the mixture of nanoparticles.
Michael Whitcombe   +2 more
exaly   +4 more sources

Lymphocyte memory and affinity selection

Journal of Theoretical Biology, 1995
The persistence of antigen-specific immune memory appears to require the presence of antigen--suggesting that memory may be due to restimulation of "memory" lymphocytes by persisting antigen. Persistence of antigen, in a form capable of stimulating B cell proliferation, on long-lived, follicular dendritic cells of lymphoid tissue is well documented ...
M A, Fishman, A S, Perelson
openaire   +2 more sources

Affinity selection and sequencing

Nature Chemical Biology, 2019
Powerful combinatorial peptide library methods allow the discovery of peptide leads from diverse libraries. A new platform based on tandem mass spectrometry peptide sequencing coupled with high-performance size-exclusion chromatography enables identification of high-affinity peptidic ligands from focused libraries.
openaire   +2 more sources

Ergoline derivatives: receptor affinity and selectivity

Il Farmaco, 1999
Ergot comprises a group of indole alkaloids which are predominantly found in various species of the ascomycete Claviceps. In pharmacopoeias, the sclerotia of Claviceps purpurea (Fr.) Tulasne parasitizing on rye, Secale cereale L., are designed as ergot or Secale cornutum.
S, Mantegani, E, Brambilla, M, Varasi
openaire   +2 more sources

Affine projection algorithm with selective projections

Signal Processing, 2012
In the affine projection adaptive filtering algorithm, convergence is sped up by increasing the projection order but with an unwelcome consequence of increased steady-state misalignment. To address this unfavorable compromise, we propose a new affine projection algorithm with selective projections. This algorithm adaptively changes the projection order
Reza Arablouei, Kutluyil Dogançay
openaire   +1 more source

Affine Projection Algorithm with Selective Regressors

2006 IEEE International Conference on Acoustics Speed and Signal Processing Proceedings, 2006
Affine projection algorithm, which updates the weight vector based on several previous input vectors, is an useful adaptive filter to improve the convergence speed of LMS-type filter. However, the computational complexity of adaptation algorithm highly depends on the number of input vectors used for update.
Kyu-Young Hwang, Woo-Jin Song
openaire   +1 more source

Driving Affinity Selection by Centrifugal Force

ASSAY and Drug Development Technologies, 2003
We describe a new approach to affinity selection based on the application of centrifugal force to macromolecules in solution. The method relies on the well known macromolecular hydrodynamic principles of centrifugation. It can be automated and operated in a centralized fashion, or it can be decentralized and used by single researchers or networks of ...
J E, Harlan   +6 more
openaire   +2 more sources

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